Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DYRK1A | Q13627 | 1/20 | 0.55 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.53 |
| ▸ | PIK3CD | O00329 | 3/20 | 0.51 |
| ▸ | PIK3CA | P42336 | 2/20 | 0.47 |
| ▸ | USP30 | Q70CQ3 | 4/20 | 0.45 |
| ▸ | MAPK7 | Q13164 | 1/20 | 0.45 |
| ▸ | MET | P08581 | 1/20 | 0.45 |
| ▸ | STS | P08842 | 1/20 | 0.45 |
| ▸ | NOS3 | P29474 | 1/20 | 0.45 |
| ▸ | NOS1 | P29475 | 1/20 | 0.45 |
| ▸ | NOS2 | P35228 | 1/20 | 0.45 |
| ▸ | HTR1A | P08908 | 1/20 | 0.44 |
| ▸ | ADRA1D | P25100 | 1/20 | 0.44 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.44 |
| ▸ | ADRA1B | P35368 | 1/20 | 0.44 |
| ▸ | CNR1 | P21554 | 2/20 | 0.44 |
| ▸ | BRD4 | O60885 | 1/20 | 0.43 |
| ▸ | KDR | P35968 | 1/20 | 0.43 |
| ▸ | CLK2 | P49760 | 1/20 | 0.43 |
| ▸ | IRAK1 | P51617 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28834146 | 1.00 | DYRK1A (0.55) | DYRK1AALDH1A1PIK3CDPIK3CAUSP30 | |
| SCHEMBL29933647 | 0.93 | PIK3CD (0.55) | DYRK1AALDH1A1PIK3CDPIK3CAUSP30 | |
| SCHEMBL28834193 | 0.93 | PIK3CD (0.55) | DYRK1AALDH1A1PIK3CDPIK3CAUSP30 | |
| SCHEMBL28834195 | 0.93 | PIK3CD (0.55) | DYRK1AALDH1A1PIK3CDPIK3CAUSP30 | |
| SCHEMBL29862549 | 0.88 | PIK3CD (0.50) | DYRK1AALDH1A1PIK3CDPIK3CAUSP30 | |
| SCHEMBL28834287 | 0.88 | PIK3CD (0.50) | DYRK1AALDH1A1PIK3CDPIK3CAUSP30 | |
| SCHEMBL28833963 | 0.88 | PIK3CD (0.50) | DYRK1AALDH1A1PIK3CDPIK3CAUSP30 | |
| SCHEMBL28833965 | 0.88 | PIK3CD (0.50) | DYRK1AALDH1A1PIK3CDPIK3CAUSP30 | |
| SCHEMBL29862676 | 0.88 | PIK3CD (0.50) | DYRK1AALDH1A1PIK3CDPIK3CAUSP30 | |
| SCHEMBL23360216 | 0.87 | HTR1A (0.48) | DYRK1AALDH1A1MAPK7NOS3NOS1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-114867719-B | Pyrrolidine and piperidine compounds | 柳韩洋行 | 2024-06-25 | — | — | CN | disclosed |
| CN-114867719-A | Pyrrolidine and piperidine compounds | 柳韩洋行 | 2022-08-05 | — | — | CN | disclosed |