Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BRD4 | O60885 | 2/20 | 0.49 |
| ▸ | USP30 | Q70CQ3 | 5/20 | 0.49 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.48 |
| ▸ | PRMT5 | O14744 | 1/20 | 0.46 |
| ▸ | BTK | Q06187 | 1/20 | 0.46 |
| ▸ | CCR8 | P51685 | 2/20 | 0.46 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.43 |
| ▸ | PIK3CD | O00329 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 2/20 | 0.42 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.42 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.42 |
| ▸ | NTSR1 | P30989 | 1/20 | 0.42 |
| ▸ | PIK3CA | P42336 | 1/20 | 0.42 |
| ▸ | TACR1 | P25103 | 1/20 | 0.42 |
| ▸ | MEN1 | O00255 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.42 |
| ▸ | POLB | P06746 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28834242 | 1.00 | BRD4 (0.49) | BRD4USP30EPHX2PRMT5BTK | |
| SCHEMBL29862551 | 1.00 | BRD4 (0.49) | BRD4USP30EPHX2PRMT5BTK | |
| SCHEMBL23360351 | 0.95 | PRMT5 (0.51) | BRD4USP30EPHX2PRMT5CCR8 | |
| SCHEMBL28834101 | 0.90 | EPHX2 (0.51) | BRD4USP30EPHX2BTKPIK3CD | |
| SCHEMBL28834100 | 0.90 | EPHX2 (0.51) | BRD4USP30EPHX2BTKPIK3CD | |
| SCHEMBL29862672 | 0.90 | EPHX2 (0.51) | BRD4USP30EPHX2BTKPIK3CD | |
| SCHEMBL23360578 | 0.89 | SLC40A1 (0.45) | EPHX2PRMT5CCR8MEN1ALDH1A1 | |
| SCHEMBL23360576 | 0.89 | SLC40A1 (0.45) | EPHX2PRMT5CCR8MEN1ALDH1A1 | |
| SCHEMBL29862661 | 0.88 | USP30 (0.49) | USP30EPHX2BTKPIK3CDMAPK1 | |
| SCHEMBL28834155 | 0.88 | USP30 (0.49) | USP30EPHX2BTKPIK3CDMAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-114867719-B | Pyrrolidine and piperidine compounds | 柳韩洋行 | 2024-06-25 | — | — | CN | disclosed |
| CN-114867719-A | Pyrrolidine and piperidine compounds | 柳韩洋行 | 2022-08-05 | — | — | CN | disclosed |