Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PREP | P48147 | 2/20 | 0.45 |
| ▸ | DRD2 | P14416 | 1/20 | 0.42 |
| ▸ | DRD4 | P21917 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
| ▸ | ENPP2 | Q13822 | 4/20 | 0.41 |
| ▸ | HCRTR1 | O43613 | 1/20 | 0.41 |
| ▸ | HCRTR2 | O43614 | 1/20 | 0.41 |
| ▸ | UTS2R | Q9UKP6 | 1/20 | 0.40 |
| ▸ | MCHR1 | Q99705 | 2/20 | 0.40 |
| ▸ | CCNT1 | O60563 | 1/20 | 0.39 |
| ▸ | CDK9 | P50750 | 1/20 | 0.39 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.39 |
| ▸ | ACE | P12821 | 1/20 | 0.39 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.39 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.39 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.39 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.39 |
| ▸ | S1PR5 | Q9H228 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28834365 | 1.00 | PREP (0.45) | PREPDRD2DRD4ALDH1A1SMN1; SMN2 | |
| SCHEMBL23378787 | 0.87 | PREP (0.45) | PREPDRD2DRD4ALDH1A1SMN1; SMN2 | |
| SCHEMBL23378788 | 0.84 | PREP (0.66) | PREP | |
| SCHEMBL23359719 | 0.84 | PREP (0.66) | PREP | |
| SCHEMBL23359723 | 0.84 | PREP (0.66) | PREP | |
| SCHEMBL29862535 | 0.84 | PREP (0.66) | PREP | |
| SCHEMBL29862589 | 0.83 | HRH1 (0.53) | ALDH1A1SMN1; SMN2ACE | |
| SCHEMBL29862512 | 0.83 | HCRTR1 (0.46) | PREPDRD2DRD4ALDH1A1SMN1; SMN2 | |
| SCHEMBL29862585 | 0.79 | POLB (0.46) | ALDH1A1SMN1; SMN2ACE | |
| SCHEMBL23379262 | 0.77 | HCRTR1 (0.54) | PREPENPP2HCRTR1HCRTR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-114867719-A | Pyrrolidine and piperidine compounds | 柳韩洋行 | 2022-08-05 | — | — | CN | disclosed |