Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 4/20 | 0.42 |
| ▸ | PKM | P14618 | 1/20 | 0.42 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.42 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.42 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.42 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.42 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.41 |
| ▸ | KAT6A | Q92794 | 2/20 | 0.40 |
| ▸ | LMNA | P02545 | 2/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | HTT | P42858 | 1/20 | 0.40 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.40 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.40 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.40 |
| ▸ | FBP1 | P09467 | 6/20 | 0.40 |
| ▸ | PGR | P06401 | 1/20 | 0.39 |
| ▸ | FLT1 | P17948 | 1/20 | 0.39 |
| ▸ | FLT4 | P35916 | 1/20 | 0.39 |
| ▸ | KDR | P35968 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28104608 | 0.87 | MRGPRX4 (0.43) | MAPTPKMCYP1A2CYP3A4CYP2D6 | |
| SCHEMBL28104316 | 0.80 | POLB (0.52) | MAPTPKMCYP1A2CYP2D6CYP2C19 | |
| SCHEMBL1648166 | 0.79 | MAPT (0.40) | MAPTPKMCYP1A2CYP3A4CYP2D6 | |
| SCHEMBL28104286 | 0.77 | KMT2A (0.43) | MAPTMAPK1LMNAKMT2AMEN1 | |
| SCHEMBL28104661 | 0.76 | CYP3A4 (0.48) | CYP1A2CYP3A4CYP2D6CYP2C19KAT6A | |
| SCHEMBL28952414 | 0.76 | EGFR (0.39) | LMNAKMT2ANPSR1ALDH1A1 | |
| SCHEMBL1648321 | 0.75 | CYP1A2 (0.36) | MAPTPKMCYP1A2CYP3A4CYP2D6 | |
| SCHEMBL4912518 | 0.74 | ALDH1A1 (0.53) | MAPTLMNAKMT2AMEN1ALDH1A1 | |
| SCHEMBL28104573 | 0.74 | KMT2A (0.44) | PKMCYP1A2CYP3A4CYP2D6CYP2C19 | |
| SCHEMBL1648929 | 0.74 | ALDH1A1 (0.39) | MAPTPKMCYP1A2CYP3A4CYP2D6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-102639494-B | Sulphones and preparation and application thereof | 扎夫根公司 | 2016-11-09 | — | — | CN | disclosed |