Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10521581 | 0.81 | DRD2 (0.31) | — | |
| Tert-Butyl Formate SCHEMBL28106914 | 0.79 | TDP1 (0.42) | TDP1 | |
| Tert-Butyl Formate SCHEMBL27830226 | 0.78 | TDP1 (0.38) | TDP1 | |
| Tert-Butyl Formate SCHEMBL27830204 | 0.77 | TDP1 (0.39) | TDP1 | |
| Tert-Butyl Formate SCHEMBL28023228 | 0.76 | TDP1 (0.36) | TDP1 | |
| Tert-Butyl Formate SCHEMBL28023216 | 0.75 | TDP1 (0.38) | TDP1 | |
| Tert-Butyl Formate SCHEMBL28023824 | 0.75 | TDP1 (0.38) | TDP1 | |
| Tert-Butyl Formate SCHEMBL28023235 | 0.75 | TDP1 (0.38) | TDP1 | |
| Tert-Butyl Formate SCHEMBL27814649 | 0.75 | TDP1 (0.48) | TDP1 | |
| Tert-Butyl Formate SCHEMBL28067918 | 0.75 | TDP1 (0.41) | TDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-106103445-B | The therapeutical uses of pyrazolo [1,5-A] pyrimidine -5,7- diamine compound and they as CDK inhibitor | 癌症研究技术有限公司 | 2019-08-09 | — | — | CN | disclosed |
| CN-106103445-A | Pyrazolo [1,5 A] pyrimidine 5,7 diamine compound and their therapeutic use as CDK inhibitor | 癌症研究技术有限公司 | 2016-11-09 | — | — | CN | disclosed |