Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 11/20 | 0.63 |
| ▸ | HPGD | P15428 | 11/20 | 0.55 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.55 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.55 |
| ▸ | LMNA | P02545 | 1/20 | 0.55 |
| ▸ | MEN1 | O00255 | 2/20 | 0.54 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.54 |
| ▸ | MAPT | P10636 | 2/20 | 0.54 |
| ▸ | THRB | P10828 | 1/20 | 0.54 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.54 |
| ▸ | NPC1 | O15118 | 2/20 | 0.52 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.52 |
| ▸ | RAB9A | P51151 | 1/20 | 0.52 |
| ▸ | TSHR | P16473 | 1/20 | 0.52 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.49 |
| ▸ | GLA | P06280 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28267142 | 0.82 | ALDH1A1 (0.65) | ALDH1A1HPGDL3MBTL1SMN1; SMN2LMNA | |
| SCHEMBL1448060 | 0.81 | ALDH1A1 (0.67) | ALDH1A1HPGDL3MBTL1SMN1; SMN2LMNA | |
| SCHEMBL5243576 | 0.80 | ALDH1A1 (0.71) | ALDH1A1HPGDL3MBTL1SMN1; SMN2LMNA | |
| SCHEMBL16898143 | 0.78 | ALDH1A1 (0.73) | ALDH1A1HPGDL3MBTL1SMN1; SMN2LMNA | |
| SCHEMBL2112079 | 0.76 | ALDH1A1 (0.69) | ALDH1A1HPGDL3MBTL1SMN1; SMN2LMNA | |
| SCHEMBL13753317 | 0.75 | ALDH1A1 (0.73) | ALDH1A1HPGDL3MBTL1SMN1; SMN2LMNA | |
| SCHEMBL5717558 | 0.75 | ALDH1A1 (0.73) | ALDH1A1HPGDL3MBTL1SMN1; SMN2LMNA | |
| Hydrochloric Acid SCHEMBL10710405 | 0.74 | ALDH1A1 (0.77) | ALDH1A1HPGDL3MBTL1SMN1; SMN2LMNA | |
| SCHEMBL8790687 | 0.74 | ALDH1A1 (0.67) | ALDH1A1HPGDL3MBTL1SMN1; SMN2LMNA | |
| SCHEMBL3201536 | 0.73 | ALDH1A1 (0.83) | ALDH1A1HPGDL3MBTL1SMN1; SMN2LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-109970797-A | Hydroxyformamide derivatives and application thereof | 葛兰素史密斯克莱知识产权（第2 号）有限公司 | 2019-07-05 | — | — | CN | disclosed |
| CN-106103431-B | Hydroxycarboxamide derivatives and their use | 葛兰素史密斯克莱知识产权（第2 号）有限公司 | 2019-03-15 | — | — | CN | disclosed |
| CN-106103431-A | Hydroxycarboxamide derivatives and their use | 葛兰素史密斯克莱知识产权（第2 号）有限公司 | 2016-11-09 | — | — | CN | disclosed |