Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | USP30 | Q70CQ3 | 5/20 | 0.39 |
| ▸ | MEN1 | O00255 | 3/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
| ▸ | PKM | P14618 | 1/20 | 0.38 |
| ▸ | RORC | P51449 | 2/20 | 0.37 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.36 |
| ▸ | GPR119 | Q8TDV5 | 1/20 | 0.36 |
| ▸ | PDE2A | O00408 | 1/20 | 0.36 |
| ▸ | HPGDS | O60760 | 1/20 | 0.36 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.36 |
| ▸ | NAMPT | P43490 | 1/20 | 0.36 |
| ▸ | JAK2 | O60674 | 1/20 | 0.35 |
| ▸ | JAK1 | P23458 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15942578 | 0.90 | USP30 (0.39) | USP30MEN1KMT2AKDM4EPKM | |
| SCHEMBL12609838 | 0.90 | HDAC6 (0.40) | USP30MEN1KMT2AKDM4EPKM | |
| SCHEMBL503579 | 0.86 | USP30 (0.43) | USP30MEN1KMT2AKDM4EPKM | |
| SCHEMBL1990004 | 0.86 | USP30 (0.43) | USP30MEN1KMT2AKDM4EPKM | |
| SCHEMBL503578 | 0.86 | USP30 (0.43) | USP30MEN1KMT2AKDM4EPKM | |
| SCHEMBL12695328 | 0.85 | HPGDS (0.42) | USP30MEN1KMT2AKDM4EPKM | |
| SCHEMBL12695288 | 0.81 | HPGDS (0.41) | USP30MEN1KMT2AKDM4EPKM | |
| SCHEMBL17224933 | 0.80 | PDE2A (0.41) | USP30MEN1KMT2AKDM4EPKM | |
| SCHEMBL1624754 | 0.80 | USP30 (0.48) | USP30KDM4EPKMRORCGPR119 | |
| SCHEMBL1624752 | 0.80 | USP30 (0.48) | USP30KDM4EPKMRORCGPR119 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-114874143-A | Regulator containing pyrazole derivatives, preparation method and application thereof | 上海翰森生物医药科技有限公司 | 2022-08-09 | — | — | CN | disclosed |