Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM5A | P29375 | 4/20 | 0.41 |
| ▸ | PHF8 | Q9UPP1 | 4/20 | 0.41 |
| ▸ | KDM2A | Q9Y2K7 | 4/20 | 0.41 |
| ▸ | KDM4C | Q9H3R0 | 3/20 | 0.41 |
| ▸ | KDM7A | Q6ZMT4 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
| ▸ | HPGD | P15428 | 2/20 | 0.34 |
| ▸ | POLB | P06746 | 1/20 | 0.34 |
| ▸ | KDM4A | O75164 | 1/20 | 0.34 |
| ▸ | PTGS1 | P23219 | 3/20 | 0.34 |
| ▸ | PTGS2 | P35354 | 3/20 | 0.34 |
| ▸ | FAAH | O00519 | 1/20 | 0.34 |
| ▸ | ITGB3 | P05106 | 2/20 | 0.33 |
| ▸ | ITGA2B | P08514 | 2/20 | 0.33 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.33 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.33 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.33 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.33 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.33 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11670764 | 0.89 | MAPT (0.42) | KDM5APHF8KDM2AKDM4CKDM7A | |
| SCHEMBL11438858 | 0.87 | CYP1A2 (0.50) | KDM5APHF8KDM2AKDM4CHPGD | |
| SCHEMBL8391308 | 0.85 | KDM5A (0.37) | KDM5APHF8KDM2AKDM4CKDM7A | |
| SCHEMBL7401679 | 0.82 | HPGD (0.41) | KDM5APHF8KDM2AKDM4CKDM7A | |
| SCHEMBL2125598 | 0.82 | KDM5A (0.51) | KDM5APHF8KDM2AKDM4CKDM7A | |
| SCHEMBL10587786 | 0.81 | — | — | |
| SCHEMBL4612433 | 0.81 | — | — | |
| SCHEMBL29193847 | 0.81 | KDM5A (0.53) | KDM5APHF8KDM2AKDM4CKDM7A | |
| SCHEMBL2211491 | 0.81 | — | — | |
| SCHEMBL11669537 | 0.80 | KDM5A (0.53) | KDM5APHF8KDM2AKDM4CHPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-114874143-A | Regulator containing pyrazole derivatives, preparation method and application thereof | 上海翰森生物医药科技有限公司 | 2022-08-09 | — | — | CN | disclosed |