Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HPGD | P15428 | 2/20 | 0.41 |
| ▸ | TP53 | P04637 | 1/20 | 0.36 |
| ▸ | KDM5A | P29375 | 1/20 | 0.35 |
| ▸ | KDM7A | Q6ZMT4 | 1/20 | 0.35 |
| ▸ | KDM4C | Q9H3R0 | 1/20 | 0.35 |
| ▸ | PHF8 | Q9UPP1 | 1/20 | 0.35 |
| ▸ | KDM2A | Q9Y2K7 | 1/20 | 0.35 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 2/20 | 0.34 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.33 |
| ▸ | PLG | P00747 | 1/20 | 0.33 |
| ▸ | PLAT | P00750 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | ATM | Q13315 | 1/20 | 0.33 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.33 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.33 |
| ▸ | GAA | P10253 | 1/20 | 0.32 |
| ▸ | NPC1 | O15118 | 1/20 | 0.32 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11670009 | 0.86 | HPGD (0.57) | HPGDTP53MAPTHSD11B1ALDH1A1 | |
| SCHEMBL12511462 | 0.84 | — | — | |
| SCHEMBL8391882 | 0.84 | — | — | |
| SCHEMBL9157382 | 0.84 | — | — | |
| SCHEMBL4438928 | 0.84 | — | — | |
| SCHEMBL11670124 | 0.83 | LIPA (0.50) | HPGDMAPTHSD11B1ALDH1A1GAA | |
| SCHEMBL28835644 | 0.82 | KDM5A (0.41) | HPGDKDM5AKDM7AKDM4CPHF8 | |
| SCHEMBL11669567 | 0.82 | MAPT (0.38) | HPGDTDP1MAPTHSD11B1ALDH1A1 | |
| SCHEMBL8555451 | 0.79 | — | — | |
| SCHEMBL301024 | 0.79 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 17 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-113461657-B | Organic small molecule gel and preparation method and application thereof | 天津大学 | 2022-05-17 | — | — | CN | disclosed |
| CN-113461657-A | Organic small molecule gel and preparation method and application thereof | 天津大学 | 2021-10-01 | — | — | CN | disclosed |
| CN-104592250-B | A kind of environment-friendly preparation method of prasugrel cheaply | XINFA PHARMACEUTICAL CO., LTD. (CN) | 2016-05-11 | — | — | CN | disclosed |
| CN-103121933-B | 4-hydroxyl-3-hexanone catalytic dehydration method | SINOPEC CORP. (CN) | 2016-01-13 | — | — | CN | disclosed |
| CN-103121931-B | Method for producing 4-hexene-3-one by dehydration of 4-hydroxyl-3-hexanone | CHINA PETROLEUM & CHEMICAL | 2015-05-13 | — | — | CN | disclosed |
| CN-103121929-B | Method for producing 4-hexene-3-one by dehydration of 4-hydroxyl-3-hexanone | CHINA PETROLEUM & CHEMICAL | 2015-05-13 | — | — | CN | disclosed |
| CN-103121930-B | Method of catalytic dehydration by 4-hydroxyl-3-hexanone | CHINA PETROLEUM & CHEMICAL | 2015-04-08 | — | — | CN | disclosed |
| CN-103121932-B | Catalytic dehydrating preparation method of 4-hexen-3-ketone by 4- hydroxy-3-hexanone | CHINA PETROLEUM & CHEMICAL | 2015-04-08 | — | — | CN | disclosed |
| CN-104379617-A | Polymer compound, resin composition for photoresists, and method for producing semiconductor | DAICEL CORP0RATION | 2015-02-25 | — | — | CN | disclosed |
| CN-103058838-B | Preparation method of 4-hexene-3-ketone by virtue of dehydration of 4-hydroxy-3-hexanone | CHINA PETROLEUM & CHEMICAL | 2015-02-11 | — | — | CN | disclosed |
| US-6169181-B1 | HUMAN IMMUNODEFICIENCY VIRUS PROTEINASE INHIBITORS | PHARMACIA & UPJOHN COMPANY | 2001-01-02 | — | — | US | disclosed |
| US-5852195-A | Pyranone compounds useful to treat retroviral infections | PHARMACIA & UPJOHN COMPANY (US) | 1998-12-22 | — | — | US | disclosed |
| EP-0758327-A1 | PYRANONE COMPOUNDS USEFUL TO TREAT RETROVIRAL INFECTIONS | PHARMACIA & UPJOHN COMPANY (US) | 1997-02-19 | — | — | EP | disclosed |
| WO-1995030670-A2 | PYRANONE COMPOUNDS USEFUL TO TREAT RETROVIRAL INFECTIONS | PHARMACIA & UPJOHN COMPANY (US) | 1995-11-16 | — | — | WO | disclosed |
| EP-0223327-B1 | TRIAZOLYLMETHYL-TERT.-BUTYL-CARBINOL DERIVATIVES, PROCESSES FOR THEIR PREPARATION AND THEIR USE AS PLANT GROWTH REGULATORS | IMPERIAL CHEMICAL INDUSTRIES PLC (GB) | 1991-10-16 | — | — | EP | disclosed |
| US-4999043-A | Triazolylmethyl tert-butyl carbinol derivatives which have plant growth regulating properties | IMPERIAL CHEMICAL INDUSTRIES PLC (GB) | 1991-03-12 | — | — | US | disclosed |
| EP-0223327-A1 | Triazolylmethyl-tert.-butyl-carbinol derivatives, processes for their preparation and their use as plant growth regulators | IMPERIAL CHEMICAL INDUSTRIES PLC (GB) | 1987-05-27 | — | — | EP | disclosed |