Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HCAR2 | Q8TDS4 | 3/20 | 0.49 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.48 |
| ▸ | POLB | P06746 | 1/20 | 0.47 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.45 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.43 |
| ▸ | KDM5B | Q9UGL1 | 1/20 | 0.41 |
| ▸ | ALPL | P05186 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 3/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.38 |
| ▸ | NPC1 | O15118 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | TP53 | P04637 | 1/20 | 0.38 |
| ▸ | XBP1 | P17861 | 1/20 | 0.38 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.38 |
| ▸ | HTT | P42858 | 1/20 | 0.38 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.38 |
| ▸ | TLR9 | Q9NR96 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2869702 | 0.87 | KDM4E (0.46) | HCAR2KDM4EPOLBPDE4DL3MBTL1 | |
| SCHEMBL9941259 | 0.83 | KDM4E (0.50) | HCAR2KDM4EPOLBPDE4DL3MBTL1 | |
| SCHEMBL2846088 | 0.83 | HCAR2 (0.59) | HCAR2KDM4EPOLBPDE4DL3MBTL1 | |
| SCHEMBL9025212 | 0.83 | HCAR2 (0.66) | HCAR2KDM4EPOLBPDE4DL3MBTL1 | |
| SCHEMBL3955623 | 0.80 | HCAR2 (0.65) | HCAR2KDM4EPOLBPDE4DMAPT | |
| SCHEMBL28835744 | 0.79 | HCAR2 (0.65) | HCAR2 | |
| SCHEMBL3463424 | 0.76 | KDM4E (0.44) | HCAR2KDM4EPOLBPDE4DL3MBTL1 | |
| SCHEMBL28835673 | 0.75 | KDM4E (0.43) | HCAR2KDM4EPOLBPDE4DL3MBTL1 | |
| SCHEMBL28835610 | 0.75 | POLB (0.46) | HCAR2KDM4EPOLBPDE4DL3MBTL1 | |
| SCHEMBL5750124 | 0.74 | L3MBTL1 (0.47) | HCAR2KDM4EPOLBL3MBTL1KDM5B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-114874143-A | Regulator containing pyrazole derivatives, preparation method and application thereof | 上海翰森生物医药科技有限公司 | 2022-08-09 | — | — | CN | disclosed |