Phenylacetic Acid

Phenylacetic Acid

SCHEMBL28835698

COC(=O)C(CO)c1ccccc1.O=C(O)Cc1ccccc1

nearest known ligand 0.52

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
AKR1B1 P15121 1/20 0.52
KMT2A Q03164 3/20 0.49
MEN1 O00255 2/20 0.47
CHRM2 P08172 3/20 0.45
CHRM1 P11229 3/20 0.45
CHRM5 P08912 2/20 0.45
CHRM3 P20309 2/20 0.45
HTR2C P28335 2/20 0.45
BLM P54132 2/20 0.45
KDM4E B2RXH2 1/20 0.45
LMNA P02545 1/20 0.45
POLB P06746 1/20 0.45
ADRA2C P18825 1/20 0.45
ADRA1A P35348 1/20 0.45
HRH1 P35367 1/20 0.45
NFKB1 P19838 1/20 0.45
SLC22A1 O15245 1/20 0.45
CHRM4 P08173 1/20 0.45
ADRA1D P25100 1/20 0.45
ALDH1A1 P00352 1/20 0.45

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL5812804 0.89 KMT2A (0.60) KMT2AMEN1CHRM2CHRM1CHRM5
SCHEMBL30870371 0.89 KMT2A (0.60) KMT2AMEN1CHRM2CHRM1CHRM5
SCHEMBL11040087 0.83 MAPT (0.53) KMT2AMEN1CHRM2CHRM1CHRM5
Benzoic Acid SCHEMBL28108053 0.81 KMT2A (0.51) KMT2AMEN1CHRM2CHRM1CHRM5
SCHEMBL1234209 0.79 ESR1 (0.68) KMT2AMEN1CHRM1POLBALDH1A1
SCHEMBL6681008 0.77 KMT2A (0.58) KMT2AMEN1ALDH1A1ESR1ESR2
SCHEMBL27496475 0.76 KMT2A (0.53) KMT2AMEN1CHRM1POLBALDH1A1
SCHEMBL27494792 0.76 ALDH1A1 (0.52) KMT2AMEN1CHRM2CHRM1CHRM5
SCHEMBL21634088 0.76 ALDH1A1 (0.52) KMT2AMEN1CHRM2CHRM1CHRM5
Phenylacetic Acid SCHEMBL27794926 0.76 AKR1B1 (0.61) AKR1B1LMNAALDH1A1CNR2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-105985241-A Inhibition effect of [alpha]-substituted phenyl acetate compounds on [alpha]-glycosidase and application of the compounds 邵阳学院 2016-10-05 CN claimed
CN-105985241-A Inhibition effect of [alpha]-substituted phenyl acetate compounds on [alpha]-glycosidase and application of the compounds 邵阳学院 2016-10-05 CN disclosed