Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 2/20 | 0.35 |
| ▸ | GAA | P10253 | 1/20 | 0.35 |
| ▸ | ALOX5AP | P20292 | 13/20 | 0.34 |
| ▸ | FEN1 | P39748 | 12/20 | 0.34 |
| ▸ | PARP10 | Q53GL7 | 1/20 | 0.34 |
| ▸ | PARP11 | Q9NR21 | 1/20 | 0.34 |
| ▸ | CYP17A1 | P05093 | 2/20 | 0.32 |
| ▸ | CYP11B1 | P15538 | 2/20 | 0.32 |
| ▸ | CYP11B2 | P19099 | 2/20 | 0.32 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.32 |
| ▸ | CLK1 | P49759 | 1/20 | 0.31 |
| ▸ | DYRK1A | Q13627 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29782326 | 1.00 | LMNA (0.35) | LMNAGAAALOX5APFEN1PARP10 | |
| SCHEMBL19551435 | 0.86 | LMNA (0.43) | LMNAGAAALOX5APFEN1PARP10 | |
| SCHEMBL29718880 | 0.86 | LMNA (0.43) | LMNAGAAALOX5APFEN1PARP10 | |
| SCHEMBL19551436 | 0.86 | LMNA (0.43) | LMNAGAAALOX5APFEN1PARP10 | |
| SCHEMBL19552828 | 0.78 | ALOX5AP (0.41) | ALOX5APFEN1PARP10PARP11CYP17A1 | |
| SCHEMBL29718754 | 0.77 | ALOX5AP (0.36) | LMNAGAAALOX5APFEN1 | |
| SCHEMBL20916494 | 0.77 | ALOX5AP (0.36) | LMNAGAAALOX5APFEN1 | |
| SCHEMBL20916495 | 0.77 | ALOX5AP (0.36) | LMNAGAAALOX5APFEN1 | |
| SCHEMBL29718530 | 0.77 | HDAC4 (0.34) | ALOX5APFEN1 | |
| SCHEMBL19551705 | 0.76 | PDE3B (0.33) | LMNAGAAALOX5APFEN1DYRK1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115054600-A | Aromatic sulfonamide derivatives | 拜耳制药股份公司 | 2022-09-16 | — | — | CN | disclosed |
| CN-114984003-A | Aromatic sulfonamide derivatives | 拜耳制药股份公司 | 2022-09-02 | — | — | CN | disclosed |