Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HRH3 | Q9Y5N1 | 19/20 | 0.65 |
| ▸ | DRD2 | P14416 | 1/20 | 0.48 |
| ▸ | DRD4 | P21917 | 1/20 | 0.48 |
| ▸ | DRD3 | P35462 | 1/20 | 0.48 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28836299 | 0.92 | HRH3 (0.71) | HRH3DRD2DRD4DRD3KCNH2 | |
| SCHEMBL29783123 | 0.92 | HRH3 (0.71) | HRH3DRD2DRD4DRD3KCNH2 | |
| SCHEMBL28836214 | 0.84 | DRD3 (0.51) | HRH3DRD2DRD4DRD3 | |
| SCHEMBL8161846 | 0.79 | HRH3 (0.67) | HRH3DRD2DRD4DRD3 | |
| SCHEMBL3646548 | 0.79 | HRH3 (1.00) | HRH3KCNH2 | |
| SCHEMBL8154261 | 0.79 | HRH3 (0.95) | HRH3KCNH2 | |
| SCHEMBL8548891 | 0.78 | PRMT5 (0.53) | HRH3DRD2DRD4DRD3 | |
| SCHEMBL8159331 | 0.78 | HRH3 (0.73) | HRH3DRD2DRD4DRD3KCNH2 | |
| SCHEMBL582220 | 0.77 | GRM5 (0.51) | HRH3 | |
| SCHEMBL29783006 | 0.77 | TNIK (0.55) | HRH3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-114989085-B | Aryl lactam ring compound, pharmaceutical composition and application thereof | 安徽医科大学 | 2023-11-24 | — | — | CN | disclosed |
| CN-114989085-A | Aryl lactam ring compound, pharmaceutical composition and application thereof | 安徽医科大学 | 2022-09-02 | — | — | CN | disclosed |