Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HRH3 | Q9Y5N1 | 18/20 | 0.71 |
| ▸ | DRD2 | P14416 | 1/20 | 0.54 |
| ▸ | DRD4 | P21917 | 1/20 | 0.54 |
| ▸ | DRD3 | P35462 | 1/20 | 0.54 |
| ▸ | GRM5 | P41594 | 1/20 | 0.51 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29783123 | 1.00 | HRH3 (0.71) | HRH3DRD2DRD4DRD3GRM5 | |
| SCHEMBL28836262 | 0.92 | HRH3 (0.65) | HRH3DRD2DRD4DRD3KCNH2 | |
| SCHEMBL8161846 | 0.86 | HRH3 (0.67) | HRH3DRD2DRD4DRD3GRM5 | |
| SCHEMBL8159331 | 0.85 | HRH3 (0.73) | HRH3DRD2DRD4DRD3GRM5 | |
| SCHEMBL582220 | 0.84 | GRM5 (0.51) | HRH3GRM5 | |
| SCHEMBL3646548 | 0.83 | HRH3 (1.00) | HRH3KCNH2 | |
| SCHEMBL8154261 | 0.83 | HRH3 (0.95) | HRH3GRM5KCNH2 | |
| SCHEMBL10244016 | 0.83 | HRH3 (0.70) | HRH3DRD2DRD4DRD3GRM5 | |
| SCHEMBL2627965 | 0.81 | GRM5 (0.48) | HRH3DRD2GRM5 | |
| SCHEMBL8162038 | 0.81 | HRH3 (0.82) | HRH3GRM5KCNH2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-114989085-B | Aryl lactam ring compound, pharmaceutical composition and application thereof | 安徽医科大学 | 2023-11-24 | — | — | CN | disclosed |
| CN-114989085-A | Aryl lactam ring compound, pharmaceutical composition and application thereof | 安徽医科大学 | 2022-09-02 | — | — | CN | disclosed |