Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LCK | P06239 | 4/20 | 0.61 |
| ▸ | NQO2 | P16083 | 4/20 | 0.58 |
| ▸ | PTPN1 | P18031 | 3/20 | 0.57 |
| ▸ | KDM1A | O60341 | 1/20 | 0.54 |
| ▸ | ALOX12 | P18054 | 2/20 | 0.52 |
| ▸ | MAPT | P10636 | 2/20 | 0.52 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.52 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.52 |
| ▸ | RGS12 | O14924 | 1/20 | 0.52 |
| ▸ | TP53 | P04637 | 1/20 | 0.52 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.52 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.52 |
| ▸ | PKM | P14618 | 1/20 | 0.52 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.52 |
| ▸ | CASP1 | P29466 | 1/20 | 0.52 |
| ▸ | THPO | P40225 | 1/20 | 0.52 |
| ▸ | GNAI1 | P63096 | 1/20 | 0.52 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.52 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.52 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28111532 | 0.87 | KDM1A (0.56) | LCKNQO2PTPN1KDM1AALOX12 | |
| SCHEMBL6377504 | 0.81 | HDAC6 (0.57) | PTPN1MAPTKDM4EPOLBHDAC6 | |
| SCHEMBL10335571 | 0.80 | LCK (0.94) | LCKNQO2PTPN1KDM1AALOX12 | |
| SCHEMBL28111445 | 0.80 | KDM1A (0.61) | LCKNQO2PTPN1KDM1AMAPT | |
| SCHEMBL28111933 | 0.79 | KDM1A (0.59) | LCKPTPN1KDM1AMAPTALDH1A1 | |
| SCHEMBL30631591 | 0.78 | LCK (1.00) | LCKNQO2PTPN1ALOX12MAPT | |
| SCHEMBL31706727 | 0.78 | LCK (1.00) | LCKNQO2PTPN1ALOX12MAPT | |
| SCHEMBL1824175 | 0.78 | LCK (1.00) | LCKNQO2PTPN1ALOX12MAPT | |
| SCHEMBL1824176 | 0.78 | LCK (1.00) | LCKNQO2PTPN1ALOX12MAPT | |
| SCHEMBL4255519 | 0.75 | LCK (0.74) | LCKNQO2PTPN1KDM1AALOX12 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-106045881-A | Resveratrol derivative, preparation method thereof and application of resveratrol derivative serving as LSD1 inhibitor | 新乡医学院 | 2016-10-26 | — | — | CN | disclosed |