Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM1A | O60341 | 4/20 | 0.61 |
| ▸ | MAPT | P10636 | 2/20 | 0.47 |
| ▸ | SNCA | P37840 | 1/20 | 0.47 |
| ▸ | NPC1 | O15118 | 1/20 | 0.46 |
| ▸ | MTOR | P42345 | 1/20 | 0.46 |
| ▸ | BACE1 | P56817 | 2/20 | 0.43 |
| ▸ | APP | P05067 | 4/20 | 0.39 |
| ▸ | PRMT5 | O14744 | 1/20 | 0.38 |
| ▸ | PRMT1 | Q99873 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | HPGD | P15428 | 1/20 | 0.38 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.38 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.38 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.38 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.38 |
| ▸ | LCK | P06239 | 2/20 | 0.36 |
| ▸ | IGF1R | P08069 | 1/20 | 0.36 |
| ▸ | NQO2 | P16083 | 1/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | POLB | P06746 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28111933 | 0.83 | KDM1A (0.59) | KDM1AMAPTSNCAPRMT5PRMT1 | |
| SCHEMBL28836345 | 0.80 | LCK (0.61) | KDM1AMAPTSNCANPC1MTOR | |
| SCHEMBL28111394 | 0.76 | KDM1A (0.58) | KDM1AMAPTSNCANPC1MTOR | |
| SCHEMBL28111395 | 0.76 | KDM1A (0.58) | KDM1AMAPTSNCANPC1MTOR | |
| SCHEMBL31236624 | 0.76 | KDM1A (1.00) | KDM1AMAPTSNCANPC1MTOR | |
| SCHEMBL28111447 | 0.76 | KDM1A (1.00) | KDM1AMAPTSNCANPC1MTOR | |
| SCHEMBL28111532 | 0.69 | KDM1A (0.56) | KDM1AMAPTNPC1MTORALDH1A1 | |
| SCHEMBL12348299 | 0.69 | HSD17B10 (0.36) | PRMT5PRMT1ALDH1A1HPGDCYP2C19 | |
| SCHEMBL6377504 | 0.68 | HDAC6 (0.57) | MAPTSNCAAPPPTPN1KDM4E | |
| SCHEMBL1226703 | 0.66 | ALDH1A1 (0.48) | KDM1APRMT5PRMT1ALDH1A1HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-106045881-A | Resveratrol derivative, preparation method thereof and application of resveratrol derivative serving as LSD1 inhibitor | 新乡医学院 | 2016-10-26 | — | — | CN | disclosed |