Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MGAM | O43451 | 7/20 | 0.71 |
| ▸ | AMY1A | P0DUB6 | 7/20 | 0.71 |
| ▸ | GAA | P10253 | 7/20 | 0.71 |
| ▸ | SI | P14410 | 7/20 | 0.71 |
| ▸ | MGAM2 | Q2M2H8 | 7/20 | 0.71 |
| ▸ | F12 | P00748 | 4/20 | 0.71 |
| ▸ | HDAC3 | O15379 | 2/20 | 0.56 |
| ▸ | HDAC4 | P56524 | 2/20 | 0.56 |
| ▸ | HDAC1 | Q13547 | 2/20 | 0.56 |
| ▸ | HDAC7 | Q8WUI4 | 2/20 | 0.56 |
| ▸ | HDAC2 | Q92769 | 2/20 | 0.56 |
| ▸ | HDAC10 | Q969S8 | 2/20 | 0.56 |
| ▸ | HDAC11 | Q96DB2 | 2/20 | 0.56 |
| ▸ | HDAC8 | Q9BY41 | 2/20 | 0.56 |
| ▸ | HDAC6 | Q9UBN7 | 2/20 | 0.56 |
| ▸ | HDAC9 | Q9UKV0 | 2/20 | 0.56 |
| ▸ | HDAC5 | Q9UQL6 | 2/20 | 0.56 |
| ▸ | FAAH | O00519 | 1/20 | 0.53 |
| ▸ | MGLL | Q99685 | 1/20 | 0.53 |
| ▸ | KMT2A | Q03164 | 6/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29728228 | 1.00 | MGAM (0.71) | MGAMAMY1AGAASIMGAM2 | |
| SCHEMBL29728226 | 0.84 | MGAM (0.52) | MGAMAMY1AGAASIMGAM2 | |
| SCHEMBL28836588 | 0.84 | MGAM (0.52) | MGAMAMY1AGAASIMGAM2 | |
| SCHEMBL28836684 | 0.83 | SMN1; SMN2 (0.57) | MGAMAMY1AGAASIMGAM2 | |
| SCHEMBL28952648 | 0.83 | GAA (0.65) | MGAMAMY1AGAASIMGAM2 | |
| SCHEMBL29728232 | 0.83 | GAA (0.65) | MGAMAMY1AGAASIMGAM2 | |
| SCHEMBL2494948 | 0.83 | MGAM (1.00) | MGAMAMY1AGAASIMGAM2 | |
| SCHEMBL29728242 | 0.81 | KMT2A (0.57) | MGAMAMY1AGAASIMGAM2 | |
| SCHEMBL28836692 | 0.81 | KMT2A (0.57) | MGAMAMY1AGAASIMGAM2 | |
| SCHEMBL29728237 | 0.81 | GAA (0.68) | MGAMAMY1AGAASIMGAM2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-114874141-B | Synthesis method for constructing phenanthridine compounds by ring-opening cyclization of alkenyl benzotriazole under catalysis of visible light | 河南大学 | 2024-03-29 | — | — | CN | disclosed |
| CN-114874141-A | Synthesis method for constructing phenanthridine compound through ring-opening cyclization of alkenyl benzotriazole under catalysis of visible light | 河南大学 | 2022-08-09 | — | — | CN | disclosed |