Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MGAM | O43451 | 11/20 | 1.00 |
| ▸ | AMY1A | P0DUB6 | 11/20 | 1.00 |
| ▸ | GAA | P10253 | 11/20 | 1.00 |
| ▸ | SI | P14410 | 11/20 | 1.00 |
| ▸ | MGAM2 | Q2M2H8 | 11/20 | 1.00 |
| ▸ | F12 | P00748 | 6/20 | 1.00 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.70 |
| ▸ | HPGD | P15428 | 2/20 | 0.70 |
| ▸ | F2 | P00734 | 1/20 | 0.70 |
| ▸ | SLC9A1 | P19634 | 1/20 | 0.70 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.68 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.68 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.68 |
| ▸ | MAPT | P10636 | 1/20 | 0.68 |
| ▸ | HTT | P42858 | 1/20 | 0.68 |
| ▸ | MEN1 | O00255 | 1/20 | 0.65 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.65 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.64 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.64 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.64 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL26095836 | 0.86 | MGAM (0.75) | MGAMAMY1AGAASIMGAM2 | |
| SCHEMBL30387510 | 0.86 | MGAM (0.75) | MGAMAMY1AGAASIMGAM2 | |
| SCHEMBL16706437 | 0.84 | MGAM (0.77) | MGAMAMY1AGAASIMGAM2 | |
| SCHEMBL29433322 | 0.83 | MGAM (1.00) | MGAMAMY1AGAASIMGAM2 | |
| SCHEMBL2493561 | 0.83 | MGAM (1.00) | MGAMAMY1AGAASIMGAM2 | |
| SCHEMBL28836741 | 0.83 | MGAM (0.71) | MGAMAMY1AGAASIMGAM2 | |
| SCHEMBL29728228 | 0.83 | MGAM (0.71) | MGAMAMY1AGAASIMGAM2 | |
| SCHEMBL6134508 | 0.82 | MGAM (0.80) | MGAMAMY1AGAASIMGAM2 | |
| SCHEMBL27397036 | 0.82 | F12 (1.00) | MGAMAMY1AGAASIMGAM2 | |
| SCHEMBL29995807 | 0.82 | MGAM (0.69) | MGAMAMY1AGAASIMGAM2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 13 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20190201414-A1 | INHIBITOR OF HEME DEGRADATION FOR USE TO IMPROVE ANTIBIOTIC TREATMENT OF MYCOBACTERIUM TUBERCULOSIS INFECTION | THE UNITED STATES OF AMERICA, AS REPRESENTED BY THE SECRETARY, DEPARTMENT OF HEALTH AND HUMAN SERV (US) | 2019-07-04 | — | — | US | disclosed |
| US-8603917-B2 | Method of processing a wafer | AGENCY FOR SCIENCE, TECHNOLOGY AND RESEARCH (SG) | 2013-12-10 | — | — | US | disclosed |
| US-8450368-B2 | Heme oxygenase inhibitors, screening methods for heme oxygenase inhibitors and methods of use of heme oxygenase inhibitors for antimicrobial therapy | UNIVERSITY OF MARYLAND, BALTIMORE (US) | 2013-05-28 | — | — | US | disclosed |
| US-8450368-B2 | Heme oxygenase inhibitors, screening methods for heme oxygenase inhibitors and methods of use of heme oxygenase inhibitors for antimicrobial therapy | UNIVERSITY OF MARYLAND, BALTIMORE (US) | 2013-05-28 | — | — | US | disclosed |
| US-8330039-B2 | Solar cell modules with poly(vinyl butyral) encapsulant comprising unsaturated heterocyclic compound | E I DU PONT DE NEMOURS AND COMPANY (US) | 2012-12-11 | — | — | US | disclosed |
| US-20120178258-A1 | METHOD OF PROCESSING A WAFER | AGENCY FOR SCIENCE, TECHNOLOGY AND RESEARCH | 2012-07-12 | — | — | US | disclosed |
| EP-2380208-A1 | SOLAR CELL MODULES WITH POLY(VINYL BUTYRAL) ENCAPSULANT COMPRISING UNSATURATED HETEROCYCLIC COMPOUND | E. I. du Pont de Nemours and Company (US) | 2011-10-26 | — | — | EP | disclosed |
| WO-2010085664-A1 | SOLAR CELL MODULES WITH POLY(VINYL BUTYRAL) ENCAPSULANT COMPRISING UNSATURATED HETEROCYCLIC COMPOUND | E. I. DU PONT DE NEMOURS AND COMPANY (US) | 2010-07-29 | — | — | WO | disclosed |
| US-20100180947-A1 | SOLAR CELL MODULES WITH POLY(VINYL BUTYRAL) ENCAPSULANT COMPRISING UNSATURATED HETEROCYCLIC COMPOUND | E. I. DU PONT DE NEMOURS AND COMPANY (US) | 2010-07-22 | — | — | US | disclosed |
| US-20100081661-A1 | HEME OXYGENASE INHIBITORS, SCREENING METHODS FOR HEME OXYGENASE INHIBITORS AND METHODS OF USE OF HEME OXYGENASE INHIBITORS FOR ANTIMICROBIAL THERAPY | UNIVERSITY OF MARYLAND, BALTIMORE (US) | 2010-04-01 | — | — | US | disclosed |
| US-20100081661-A1 | HEME OXYGENASE INHIBITORS, SCREENING METHODS FOR HEME OXYGENASE INHIBITORS AND METHODS OF USE OF HEME OXYGENASE INHIBITORS FOR ANTIMICROBIAL THERAPY | UNIVERSITY OF MARYLAND, BALTIMORE (US) | 2010-04-01 | — | — | US | disclosed |
| US-6608066-B1 | Treating mammal susceptible to, suffering from, suspected of having or recovering from disease impacted by tissue factor, such as cardiovascular, blood coagulation, cell proliferation or immune disorders, atherosclerosis, inflammation or cancer | SUNOL MOLECULAR CORPORATION | 2003-08-19 | — | — | US | disclosed |
| US-6608066-B1 | Treating mammal susceptible to, suffering from, suspected of having or recovering from disease impacted by tissue factor, such as cardiovascular, blood coagulation, cell proliferation or immune disorders, atherosclerosis, inflammation or cancer | SUNOL MOLECULAR CORPORATION | 2003-08-19 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100081661-A1 | HEME OXYGENASE INHIBITORS, SCREENING METHODS FOR HEME OXYGENASE INHIBITORS AND METHODS OF USE OF HEME OXYGENASE INHIBITORS FOR ANTIMICROBIAL THERAPY | HMOX1, HMOX2, PPOX | MGAM 147/4885AMY1A 2879/4885GAA 2000/4885 |
| US-20190201414-A1 | INHIBITOR OF HEME DEGRADATION FOR USE TO IMPROVE ANTIBIOTIC TREATMENT OF MYCOBACTERIUM TUBERCULOSIS INFECTION | HMOX1, HMOX2, PPOX | MGAM 679/4885AMY1A 2975/4885GAA 504/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.