Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KCNN4 | O15554 | 1/20 | 0.48 |
| ▸ | KCNA3 | P22001 | 1/20 | 0.48 |
| ▸ | HSD11B1 | P28845 | 2/20 | 0.47 |
| ▸ | CD4 | P01730 | 2/20 | 0.46 |
| ▸ | MMP2 | P08253 | 1/20 | 0.46 |
| ▸ | GAA | P10253 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 4/20 | 0.42 |
| ▸ | TP53 | P04637 | 1/20 | 0.42 |
| ▸ | CA1 | P00915 | 1/20 | 0.42 |
| ▸ | CA2 | P00918 | 1/20 | 0.42 |
| ▸ | CYP11B1 | P15538 | 1/20 | 0.41 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.41 |
| ▸ | CTSG | P08311 | 1/20 | 0.40 |
| ▸ | CMA1 | P23946 | 1/20 | 0.40 |
| ▸ | NR1H2 | P55055 | 1/20 | 0.40 |
| ▸ | NR1H3 | Q13133 | 1/20 | 0.40 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29714461 | 1.00 | KCNN4 (0.48) | KCNN4KCNA3HSD11B1CD4MMP2 | |
| SCHEMBL29101146 | 0.91 | KCNN4 (0.47) | KCNN4KCNA3HSD11B1CD4MMP2 | |
| SCHEMBL28836746 | 0.91 | KCNN4 (0.54) | KCNN4KCNA3HSD11B1CD4MMP2 | |
| SCHEMBL29714451 | 0.91 | KCNN4 (0.54) | KCNN4KCNA3HSD11B1CD4MMP2 | |
| SCHEMBL29714459 | 0.90 | KCNN4 (0.44) | KCNN4KCNA3HSD11B1CD4MMP2 | |
| SCHEMBL29714455 | 0.90 | KCNN4 (0.44) | KCNN4KCNA3HSD11B1CD4MMP2 | |
| SCHEMBL29101141 | 0.90 | KCNN4 (0.44) | KCNN4KCNA3HSD11B1CD4MMP2 | |
| SCHEMBL29101138 | 0.90 | KCNN4 (0.44) | KCNN4KCNA3HSD11B1CD4MMP2 | |
| SCHEMBL29101134 | 0.87 | KCNN4 (0.56) | KCNN4KCNA3HSD11B1CD4MMP2 | |
| SCHEMBL30688098 | 0.87 | KCNN4 (0.56) | KCNN4KCNA3HSD11B1CD4MMP2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-114716374-B | 3-bit substituted dihydroquinoline derivative and preparation method thereof | 武汉工程大学 | 2023-11-07 | — | — | CN | disclosed |
| CN-114716374-A | 3-substituted dihydroquinoline derivative and preparation method thereof | 武汉工程大学 | 2022-07-08 | — | — | CN | disclosed |