Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KCNN4 | O15554 | 1/20 | 0.54 |
| ▸ | KCNA3 | P22001 | 1/20 | 0.54 |
| ▸ | HSD11B1 | P28845 | 2/20 | 0.50 |
| ▸ | MMP2 | P08253 | 1/20 | 0.49 |
| ▸ | CD4 | P01730 | 3/20 | 0.46 |
| ▸ | GAA | P10253 | 1/20 | 0.46 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.44 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.44 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.44 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.44 |
| ▸ | P2RX4 | Q99571 | 1/20 | 0.43 |
| ▸ | CTSG | P08311 | 1/20 | 0.43 |
| ▸ | CMA1 | P23946 | 1/20 | 0.43 |
| ▸ | LMNA | P02545 | 1/20 | 0.43 |
| ▸ | NR1H2 | P55055 | 1/20 | 0.43 |
| ▸ | NR1H3 | Q13133 | 1/20 | 0.43 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 3/20 | 0.42 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.42 |
| ▸ | HTR6 | P50406 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29714451 | 1.00 | KCNN4 (0.54) | KCNN4KCNA3HSD11B1MMP2CD4 | |
| SCHEMBL29101134 | 0.96 | KCNN4 (0.56) | KCNN4KCNA3HSD11B1MMP2CD4 | |
| SCHEMBL30688098 | 0.96 | KCNN4 (0.56) | KCNN4KCNA3HSD11B1MMP2CD4 | |
| SCHEMBL29101146 | 0.92 | KCNN4 (0.47) | KCNN4KCNA3HSD11B1MMP2CD4 | |
| SCHEMBL28836779 | 0.91 | KCNN4 (0.48) | KCNN4KCNA3HSD11B1MMP2CD4 | |
| SCHEMBL29714461 | 0.91 | KCNN4 (0.48) | KCNN4KCNA3HSD11B1MMP2CD4 | |
| SCHEMBL28836780 | 0.90 | KCNN4 (0.50) | KCNN4KCNA3HSD11B1MMP2CD4 | |
| SCHEMBL29101145 | 0.90 | LMNA (0.52) | KCNN4KCNA3HSD11B1MMP2GAA | |
| SCHEMBL30688097 | 0.90 | LMNA (0.52) | KCNN4KCNA3HSD11B1MMP2GAA | |
| SCHEMBL28836783 | 0.86 | CYP11B1 (0.53) | KCNN4KCNA3MMP2POLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-114716374-B | 3-bit substituted dihydroquinoline derivative and preparation method thereof | 武汉工程大学 | 2023-11-07 | — | — | CN | disclosed |
| CN-114716374-A | 3-substituted dihydroquinoline derivative and preparation method thereof | 武汉工程大学 | 2022-07-08 | — | — | CN | disclosed |