Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.46 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.46 |
| ▸ | MEN1 | O00255 | 1/20 | 0.46 |
| ▸ | APAF1 | O14727 | 1/20 | 0.46 |
| ▸ | RGS12 | O14924 | 1/20 | 0.46 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.45 |
| ▸ | NPC1 | O15118 | 1/20 | 0.45 |
| ▸ | RAB9A | P51151 | 1/20 | 0.45 |
| ▸ | PARP10 | Q53GL7 | 4/20 | 0.44 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.42 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.41 |
| ▸ | CA1 | P00915 | 2/20 | 0.40 |
| ▸ | CA2 | P00918 | 2/20 | 0.40 |
| ▸ | PARP4 | Q9UKK3 | 2/20 | 0.40 |
| ▸ | PARP1 | P09874 | 1/20 | 0.40 |
| ▸ | PARP2 | Q9UGN5 | 1/20 | 0.40 |
| ▸ | TLR8 | Q9NR97 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27899700 | 0.93 | MEN1 (0.51) | HSD17B10MAPK1KMT2AMEN1APAF1 | |
| SCHEMBL15298872 | 0.89 | HSD17B10 (0.53) | HSD17B10MAPK1KMT2AMEN1APAF1 | |
| SCHEMBL28533240 | 0.82 | BDKRB2 (0.49) | HSD17B10MAPK1HDAC8HDAC6ALDH1A1 | |
| SCHEMBL19987509 | 0.81 | HDAC8 (0.61) | HSD17B10MAPK1KMT2AMEN1APAF1 | |
| SCHEMBL28313400 | 0.81 | MAPK1 (0.49) | HSD17B10MAPK1KMT2AMEN1APAF1 | |
| SCHEMBL22563037 | 0.81 | RARB (0.47) | KMT2AMEN1ALDH1A1 | |
| SCHEMBL10956533 | 0.79 | TP53 (0.53) | KMT2AMEN1ALDH1A1NR1I2 | |
| SCHEMBL19464655 | 0.79 | HSD17B10 (0.48) | HSD17B10MAPK1KMT2AMEN1APAF1 | |
| SCHEMBL23168986 | 0.79 | RARB (0.51) | KMT2AMEN1ALDH1A1NR1I2 | |
| Dodecane SCHEMBL9222476 | 0.78 | MEN1 (0.67) | MAPK1KMT2AMEN1APAF1RGS12 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-106278775-A | The preparation method of a kind of arylamides and purification method thereof | 温州大学 | 2017-01-04 | — | — | CN | disclosed |