Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.60 |
| ▸ | MAPT | P10636 | 6/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.46 |
| ▸ | HPGD | P15428 | 4/20 | 0.46 |
| ▸ | TP53 | P04637 | 2/20 | 0.46 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.46 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.46 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.44 |
| ▸ | ATM | Q13315 | 1/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.41 |
| ▸ | NPC1 | O15118 | 2/20 | 0.41 |
| ▸ | RAB9A | P51151 | 2/20 | 0.41 |
| ▸ | MEN1 | O00255 | 2/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.41 |
| ▸ | HTT | P42858 | 1/20 | 0.41 |
| ▸ | MAOB | P27338 | 2/20 | 0.40 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.39 |
| ▸ | POLB | P06746 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29926823 | 0.89 | L3MBTL1 (0.47) | L3MBTL1MAPTKDM4EALDH1A1HPGD | |
| SCHEMBL28837162 | 0.89 | L3MBTL1 (0.47) | L3MBTL1MAPTKDM4EALDH1A1HPGD | |
| SCHEMBL28837151 | 0.84 | TNKS (0.47) | L3MBTL1MAPTPTPN1MAOBTDP1 | |
| SCHEMBL28837144 | 0.84 | L3MBTL1 (0.43) | L3MBTL1MAPTALDH1A1PTPN1CYP1A1 | |
| SCHEMBL28837143 | 0.84 | L3MBTL1 (0.43) | L3MBTL1MAPTKDM4EALDH1A1HPGD | |
| SCHEMBL28837168 | 0.83 | CA1 (0.49) | L3MBTL1MAPTKDM4EALDH1A1CYP3A4 | |
| SCHEMBL28837146 | 0.83 | L3MBTL1 (0.41) | L3MBTL1MAPTCYP3A4PTPN1CYP1A1 | |
| SCHEMBL29927472 | 0.83 | L3MBTL1 (0.41) | L3MBTL1MAPTCYP3A4PTPN1CYP1A1 | |
| SCHEMBL29926945 | 0.83 | PTPN1 (0.46) | L3MBTL1MAPTKDM4EALDH1A1HPGD | |
| SCHEMBL29927513 | 0.82 | MAPT (0.52) | L3MBTL1MAPTHPGDTP53CYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115043802-A | Synthesis method of trifluoroethyl benzofuran compound | 温州大学 | 2022-09-13 | — | — | CN | disclosed |