Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAOB | P27338 | 6/20 | 0.47 |
| ▸ | MAOA | P21397 | 3/20 | 0.44 |
| ▸ | MAPT | P10636 | 2/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.39 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.39 |
| ▸ | HTR1A | P08908 | 2/20 | 0.38 |
| ▸ | HTR1B | P28222 | 1/20 | 0.38 |
| ▸ | DRD3 | P35462 | 1/20 | 0.36 |
| ▸ | NPC1 | O15118 | 1/20 | 0.35 |
| ▸ | HPGD | P15428 | 1/20 | 0.35 |
| ▸ | TSHR | P16473 | 1/20 | 0.35 |
| ▸ | RAB9A | P51151 | 1/20 | 0.35 |
| ▸ | PTGER1 | P34995 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17759417 | 0.84 | HTR1B (0.51) | MAOBMAPTCYP3A4CYP2A6L3MBTL1 | |
| SCHEMBL19616353 | 0.82 | MAPT (0.48) | MAOBMAOAMAPTCYP3A4CYP2A6 | |
| SCHEMBL5983374 | 0.81 | MAPT (0.49) | MAOBMAOAMAPTCYP3A4CYP2A6 | |
| SCHEMBL25422969 | 0.80 | PDCD1 (0.49) | MAOBMAOAMAPTCYP3A4CYP2A6 | |
| SCHEMBL30786890 | 0.80 | ALDH1A1 (0.46) | MAPTL3MBTL1MAPK1TDP1HTR1B | |
| SCHEMBL25425235 | 0.79 | ALDH1A1 (0.40) | MAOBMAOAMAPTCYP3A4CYP2A6 | |
| SCHEMBL25701845 | 0.78 | MAPT (0.40) | MAOBMAOAMAPTCYP3A4CYP2A6 | |
| SCHEMBL30786889 | 0.77 | HTR1B (0.47) | MAPTL3MBTL1MAPK1TDP1HTR1A | |
| SCHEMBL30786892 | 0.77 | HTR1B (0.47) | MAPTL3MBTL1MAPK1TDP1HTR1A | |
| SCHEMBL26013294 | 0.77 | MAOB (0.64) | MAOBMAOAMAPTCYP3A4CYP2A6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115043784-B | Biphenyl-1, 2, 3-triazole conjugate and preparation method and application thereof | 浙江工业大学 | 2024-04-26 | — | — | CN | disclosed |
| CN-115043784-A | Biphenyl-1, 2, 3-triazole conjugate and preparation method and application thereof | 浙江工业大学 | 2022-09-13 | — | — | CN | disclosed |