Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 5/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.44 |
| ▸ | MAPT | P10636 | 1/20 | 0.44 |
| ▸ | HPGD | P15428 | 1/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.43 |
| ▸ | CXCR2 | P25025 | 2/20 | 0.40 |
| ▸ | RAB9A | P51151 | 2/20 | 0.40 |
| ▸ | NPC1 | O15118 | 1/20 | 0.40 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.40 |
| ▸ | ALPL | P05186 | 1/20 | 0.40 |
| ▸ | CCR7 | P32248 | 1/20 | 0.40 |
| ▸ | XBP1 | P17861 | 1/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.39 |
| ▸ | MEN1 | O00255 | 2/20 | 0.39 |
| ▸ | TSHR | P16473 | 2/20 | 0.39 |
| ▸ | HAO1 | Q9UJM8 | 1/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
| ▸ | GAA | P10253 | 1/20 | 0.38 |
| ▸ | HTT | P42858 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28837260 | 1.00 | LMNA (0.44) | LMNASMN1; SMN2ALDH1A1MAPTHPGD | |
| SCHEMBL28837289 | 1.00 | LMNA (0.44) | LMNASMN1; SMN2ALDH1A1MAPTHPGD | |
| SCHEMBL28952697 | 0.97 | LMNA (0.44) | LMNASMN1; SMN2ALDH1A1MAPTHPGD | |
| SCHEMBL28837293 | 0.97 | LMNA (0.44) | LMNASMN1; SMN2ALDH1A1MAPTHPGD | |
| SCHEMBL28837274 | 0.97 | LMNA (0.44) | LMNASMN1; SMN2ALDH1A1MAPTHPGD | |
| SCHEMBL28952706 | 0.97 | LMNA (0.44) | LMNASMN1; SMN2ALDH1A1MAPTHPGD | |
| SCHEMBL11874251 | 0.91 | SMN1; SMN2 (0.50) | LMNASMN1; SMN2ALDH1A1MAPTHPGD | |
| SCHEMBL17563748 | 0.91 | SMN1; SMN2 (0.50) | LMNASMN1; SMN2ALDH1A1MAPTHPGD | |
| SCHEMBL10869938 | 0.91 | SMN1; SMN2 (0.50) | LMNASMN1; SMN2ALDH1A1MAPTHPGD | |
| SCHEMBL24831482 | 0.88 | SMN1; SMN2 (0.50) | LMNASMN1; SMN2ALDH1A1MAPTHPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-114874107-B | Amino lipid and preparation method and application thereof | 中山大学附属第七医院(深圳) | 2022-11-29 | — | — | CN | disclosed |
| CN-114874107-A | Amino lipid and preparation method and application thereof | 中山大学附属第七医院(深圳) | 2022-08-09 | — | — | CN | disclosed |