Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.43 |
| ▸ | HTR1B | P28222 | 1/20 | 0.41 |
| ▸ | HRH3 | Q9Y5N1 | 6/20 | 0.41 |
| ▸ | TOP2A | P11388 | 1/20 | 0.40 |
| ▸ | LSS | P48449 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14301472 | 0.78 | KDM4E (0.44) | KDM4EALDH1A1SMN1; SMN2HTR1BHRH3 | |
| SCHEMBL9065880 | 0.78 | LTA4H (0.42) | SMN1; SMN2 | |
| SCHEMBL5474635 | 0.76 | NR5A1 (0.46) | — | |
| SCHEMBL11367576 | 0.74 | NR5A1 (0.48) | — | |
| SCHEMBL11359592 | 0.74 | NR5A1 (0.48) | — | |
| SCHEMBL11366197 | 0.74 | NR5A1 (0.48) | — | |
| SCHEMBL11368396 | 0.74 | NR5A1 (0.48) | — | |
| SCHEMBL11368455 | 0.74 | NR5A1 (0.48) | — | |
| SCHEMBL22837835 | 0.74 | LSS (0.47) | KDM4EALDH1A1SMN1; SMN2HTR1BHRH3 | |
| SCHEMBL11270818 | 0.74 | LTA4H (0.42) | SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-114874107-B | Amino lipid and preparation method and application thereof | 中山大学附属第七医院(深圳) | 2022-11-29 | — | — | CN | disclosed |
| CN-114874107-A | Amino lipid and preparation method and application thereof | 中山大学附属第七医院(深圳) | 2022-08-09 | — | — | CN | disclosed |