Boric Acid

Boric Acid

SCHEMBL28837445

CC(=O)Nc1ccccn1.CC(C)(O)C(C)(C)O.OB(O)O

nearest known ligand 0.54

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
NPC1 O15118 6/20 0.54
RAB9A P51151 6/20 0.54
PKM P14618 2/20 0.54
GAA P10253 1/20 0.51
KDM4E B2RXH2 3/20 0.49
SMN1; SMN2 Q16637 3/20 0.47
MEN1 O00255 1/20 0.47
KMT2A Q03164 1/20 0.47
ADORA3 P0DMS8 1/20 0.47
PIM1 P11309 1/20 0.47
ADORA2A P29274 1/20 0.47
ADORA2B P29275 1/20 0.47
ADORA1 P30542 1/20 0.47
FLT3 P36888 1/20 0.47
PIM3 Q86V86 1/20 0.47
AURKB Q96GD4 1/20 0.47
ALDH1A1 P00352 1/20 0.47
HTT P42858 1/20 0.47
POLB P06746 1/20 0.47
LMNA P02545 1/20 0.45

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29740123 0.87 NPC1 (0.70) NPC1RAB9APKMGAAKDM4E
SCHEMBL114271 0.87 NPC1 (0.70) NPC1RAB9APKMGAAKDM4E
Bromide SCHEMBL11460022 0.85 NPC1 (0.68) NPC1RAB9APKMGAAKDM4E
Hydrochloric Acid SCHEMBL29440615 0.85 NPC1 (0.68) NPC1RAB9APKMGAAKDM4E
Bicarbonate SCHEMBL4653075 0.83 RAB9A (0.66) NPC1RAB9APKMGAAKDM4E
SCHEMBL28116585 0.82 GAA (0.65) NPC1RAB9APKMGAAKDM4E
Pyrrole SCHEMBL28303547 0.81 GAA (0.59) NPC1RAB9APKMGAAKDM4E
Pyridine SCHEMBL2156456 0.80 RAB9A (0.61) NPC1RAB9APKMGAAKDM4E
Trifluoroacetic Acid SCHEMBL29744959 0.79 KDM4E (0.58) NPC1RAB9APKMGAAKDM4E
Trifluoroacetic Acid SCHEMBL29744737 0.79 KDM4E (0.58) NPC1RAB9APKMGAAKDM4E

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-103601745-B Preparation method of commonly used acetamidopyridine boronic acid pinacol ester 大连联化化学有限公司 2017-01-18 CN claimed