Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HPGD | P15428 | 3/20 | 0.54 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.54 |
| ▸ | HTT | P42858 | 2/20 | 0.54 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.54 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.50 |
| ▸ | POLB | P06746 | 1/20 | 0.50 |
| ▸ | RECQL | P46063 | 1/20 | 0.50 |
| ▸ | MAPT | P10636 | 3/20 | 0.48 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.48 |
| ▸ | LMNA | P02545 | 1/20 | 0.48 |
| ▸ | CARM1 | Q86X55 | 1/20 | 0.48 |
| ▸ | IDO1 | P14902 | 2/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.47 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.47 |
| ▸ | CDK4 | P11802 | 1/20 | 0.47 |
| ▸ | CCND1 | P24385 | 1/20 | 0.47 |
| ▸ | PTGDR2 | Q9Y5Y4 | 1/20 | 0.46 |
| ▸ | TP53 | P04637 | 1/20 | 0.46 |
| ▸ | FABP4 | P15090 | 1/20 | 0.45 |
| ▸ | FABP5 | Q01469 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17894452 | 0.91 | IDO1 (0.47) | HPGDALDH1A1HTTSMN1; SMN2KDM4E | |
| SCHEMBL15619523 | 0.89 | HPGD (0.66) | HPGDALDH1A1HTTSMN1; SMN2KDM4E | |
| SCHEMBL6535934 | 0.83 | ALDH1A1 (0.59) | HPGDALDH1A1HTTSMN1; SMN2KDM4E | |
| SCHEMBL28497259 | 0.83 | HTT (0.56) | HPGDALDH1A1HTTSMN1; SMN2KDM4E | |
| SCHEMBL14397894 | 0.80 | ALDH1A1 (0.59) | HPGDALDH1A1HTTSMN1; SMN2KDM4E | |
| SCHEMBL31265581 | 0.79 | ALDH1A1 (0.68) | HPGDALDH1A1HTTSMN1; SMN2KDM4E | |
| SCHEMBL8371564 | 0.78 | POLB (0.54) | HPGDALDH1A1HTTSMN1; SMN2KDM4E | |
| SCHEMBL5880095 | 0.77 | KMT2A (0.60) | HPGDALDH1A1HTTSMN1; SMN2KDM4E | |
| SCHEMBL17894427 | 0.77 | TLR2 (0.46) | HPGDALDH1A1HTTSMN1; SMN2KDM4E | |
| SCHEMBL23680052 | 0.76 | CDK4 (0.75) | HPGDALDH1A1HTTSMN1; SMN2KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-104230845-B | Semicarbazone derivatives and application thereof | 沈阳药科大学 | 2017-01-25 | — | — | CN | disclosed |