Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MGAM | O43451 | 4/20 | 0.53 |
| ▸ | GAA | P10253 | 4/20 | 0.53 |
| ▸ | SI | P14410 | 4/20 | 0.53 |
| ▸ | MGAM2 | Q2M2H8 | 4/20 | 0.53 |
| ▸ | MAPT | P10636 | 4/20 | 0.47 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.47 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.45 |
| ▸ | MAOB | P27338 | 2/20 | 0.45 |
| ▸ | NOD2 | Q9HC29 | 1/20 | 0.45 |
| ▸ | GSTP1 | P09211 | 1/20 | 0.45 |
| ▸ | PDE4B | Q07343 | 2/20 | 0.44 |
| ▸ | PDE3B | Q13370 | 2/20 | 0.44 |
| ▸ | PDE3A | Q14432 | 2/20 | 0.44 |
| ▸ | PDE10A | Q9Y233 | 2/20 | 0.44 |
| ▸ | PDE4A | P27815 | 1/20 | 0.44 |
| ▸ | ABCB1 | P08183 | 1/20 | 0.43 |
| ▸ | MEN1 | O00255 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.43 |
| ▸ | FYN | P06241 | 1/20 | 0.43 |
| ▸ | TUBB4A | P04350 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28117898 | 0.89 | ERN1 (0.48) | MGAMGAASIMGAM2MAPT | |
| SCHEMBL28117789 | 0.89 | ABCB1 (0.50) | MGAMGAASIMGAM2MAPT | |
| SCHEMBL28117665 | 0.85 | ABCB1 (0.45) | MGAMGAASIMGAM2MAPT | |
| SCHEMBL27930273 | 0.85 | MGAM (0.50) | MGAMGAASIMGAM2MAPT | |
| SCHEMBL28117707 | 0.84 | FYN (0.50) | FYNTUBB4ATUBBTUBA3CTUBA1B | |
| SCHEMBL27912265 | 0.81 | MGAM (0.48) | MGAMGAASIMGAM2MAPT | |
| SCHEMBL28117798 | 0.81 | FYN (0.55) | MGAMGAASIMGAM2MAPT | |
| SCHEMBL28118129 | 0.78 | EPHB4 (0.46) | GAAMAPTMAPK1FYNTUBB4A | |
| SCHEMBL27930288 | 0.76 | MGAM (0.54) | MGAMGAASIMGAM2MAPT | |
| SCHEMBL28118147 | 0.76 | FYN (0.58) | FYNTUBB4ATUBBTUBA3CTUBA1B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-106279058-A | The preparation of 3,4-diaryl-1,2,5-diazole oxide and purposes | 沈阳药科大学 | 2017-01-04 | — | — | CN | disclosed |