Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ERN1 | O75460 | 1/20 | 0.48 |
| ▸ | MAOB | P27338 | 3/20 | 0.46 |
| ▸ | MAPT | P10636 | 2/20 | 0.46 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.46 |
| ▸ | FYN | P06241 | 5/20 | 0.45 |
| ▸ | BCHE | P06276 | 1/20 | 0.45 |
| ▸ | PIM1 | P11309 | 1/20 | 0.43 |
| ▸ | PIM2 | Q9P1W9 | 1/20 | 0.43 |
| ▸ | C5AR1 | P21730 | 1/20 | 0.43 |
| ▸ | MGAM | O43451 | 3/20 | 0.42 |
| ▸ | GAA | P10253 | 3/20 | 0.42 |
| ▸ | SI | P14410 | 3/20 | 0.42 |
| ▸ | MGAM2 | Q2M2H8 | 3/20 | 0.42 |
| ▸ | BMPR1A | P36894 | 1/20 | 0.42 |
| ▸ | TGFBR1 | P36897 | 1/20 | 0.42 |
| ▸ | ACVRL1 | P37023 | 1/20 | 0.42 |
| ▸ | ACVR1 | Q04771 | 1/20 | 0.42 |
| ▸ | TUBB4A | P04350 | 1/20 | 0.41 |
| ▸ | TUBB | P07437 | 1/20 | 0.41 |
| ▸ | TUBA3C | P0DPH7 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28837693 | 0.89 | MGAM (0.53) | MAOBMAPTMAPK1FYNMGAM | |
| SCHEMBL28117789 | 0.87 | ABCB1 (0.50) | MAPTMAPK1MGAMGAASI | |
| SCHEMBL28117665 | 0.84 | ABCB1 (0.45) | MAPTMAPK1MGAMGAASI | |
| SCHEMBL28118147 | 0.81 | FYN (0.58) | FYNBMPR1ATGFBR1ACVRL1ACVR1 | |
| SCHEMBL27930273 | 0.76 | MGAM (0.50) | MAOBMAPTMAPK1MGAMGAA | |
| SCHEMBL28117707 | 0.75 | FYN (0.50) | FYNTUBB4ATUBBTUBA3CTUBA1B | |
| SCHEMBL28117798 | 0.75 | FYN (0.55) | MAPTFYNMGAMGAASI | |
| SCHEMBL27912265 | 0.73 | MGAM (0.48) | MAOBMAPTMAPK1MGAMGAA | |
| SCHEMBL28837591 | 0.73 | TUBB4A (0.54) | MAPTFYNTUBB4ATUBBTUBA3C | |
| SCHEMBL723918 | 0.72 | PDE4C (0.46) | ERN1MAOBMAPTMAPK1FYN |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-106279058-A | The preparation of 3,4-diaryl-1,2,5-diazole oxide and purposes | 沈阳药科大学 | 2017-01-04 | — | — | CN | disclosed |