SCHEMBL28837797

SCHEMBL28837797

CCCCCCCCCCCCCCCCn1ccnc1OCC

nearest known ligand 0.57

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TLR8 Q9NR97 4/20 0.57
POLB P06746 3/20 0.51
ALDH1A1 P00352 2/20 0.51
KMT2A Q03164 1/20 0.51
TBXAS1 P24557 1/20 0.40
TDP1 Q9NUW8 1/20 0.38
HTT P42858 5/20 0.38
LMNA P02545 4/20 0.38
SMN1; SMN2 Q16637 3/20 0.38
KDM4E B2RXH2 3/20 0.38
MAPT P10636 2/20 0.38
NPC1 O15118 5/20 0.35
RAB9A P51151 5/20 0.35
GALR3 O60755 2/20 0.35
ATM Q13315 2/20 0.35
MAPK1 P28482 2/20 0.35
NPSR1 Q6W5P4 2/20 0.35
HSP90AA1 P07900 1/20 0.35
RAD52 P43351 1/20 0.35
PAX8 Q06710 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL10352847 0.86 TLR8 (0.61) TLR8POLBALDH1A1KMT2ATBXAS1
SCHEMBL8604833 0.81 TLR8 (0.51) TLR8POLBALDH1A1KMT2ATBXAS1
SCHEMBL9035781 0.79 TLR8 (0.47) TLR8POLBALDH1A1KMT2ATBXAS1
SCHEMBL893369 0.79 ALDH1A1 (0.59) TLR8POLBALDH1A1KMT2ATDP1
SCHEMBL25267924 0.77 ALDH1A1 (0.85) TLR8POLBALDH1A1KMT2ATBXAS1
SCHEMBL25270261 0.77 ALDH1A1 (0.85) TLR8POLBALDH1A1KMT2ATBXAS1
SCHEMBL363481 0.77 ALDH1A1 (0.85) TLR8POLBALDH1A1KMT2ATBXAS1
SCHEMBL25240227 0.77 ALDH1A1 (0.85) TLR8POLBALDH1A1KMT2ATBXAS1
SCHEMBL5287541 0.77 ALDH1A1 (0.85) TLR8POLBALDH1A1KMT2ATBXAS1
SCHEMBL2328687 0.77 ALDH1A1 (0.85) TLR8POLBALDH1A1KMT2ATBXAS1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-103616806-B Cleaning fluid for photosensitive membrane 马佳 2017-02-08 CN claimed