SCHEMBL28837826

SCHEMBL28837826

CCCCCc1c(F)c(F)c(F)c(-c2ccccc2)c1-c1ccccc1F

nearest known ligand 0.48

Predicted protein targets (top 7)

geneUniProtsupporting neighboursconfidence
GCGR P47871 9/20 0.48
DHFR P00374 1/20 0.37
HSD11B1 P28845 1/20 0.37
GNRHR P30968 1/20 0.36
GPR84 Q9NQS5 1/20 0.35
TLR8 Q9NR97 3/20 0.34
USP7 Q93009 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL31403437 0.99 GCGR (0.47) GCGRDHFRHSD11B1GNRHRGPR84
SCHEMBL31403443 0.99 GCGR (0.47) GCGRDHFRHSD11B1GNRHRGPR84
SCHEMBL31398722 0.90 GCGR (0.37) GCGRGNRHRUSP7
SCHEMBL28837822 0.84 USP7 (0.42) GCGRGNRHRUSP7
SCHEMBL30990915 0.76 GCGR (0.48) GCGRHSD11B1GPR84TLR8
SCHEMBL11454320 0.75 NPC1 (0.41)
SCHEMBL11994139 0.71 MC4R (0.44) GCGRHSD11B1
SCHEMBL5716342 0.71 GCGR (0.40) GCGRGNRHRTLR8
SCHEMBL5715539 0.71 MEN1 (0.48) GCGRTLR8
SCHEMBL5716039 0.71 MEN1 (0.48) GCGRTLR8

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-114889276-B Flexible bistable film mechanism based on photoresponse and preparation method and application thereof 东华大学 2023-02-24 CN claimed
CN-114889276-B Flexible bistable film mechanism based on photoresponse and preparation method and application thereof 东华大学 2023-02-24 CN disclosed
CN-114889276-A Flexible bistable thin film mechanism based on photoresponse and preparation method and application thereof 东华大学 2022-08-12 CN disclosed