SCHEMBL5716342

SCHEMBL5716342

CCCCCCCCCPCCCCCC.Fc1ccccc1-c1c(F)c(F)c(F)c(F)c1F

nearest known ligand 0.40

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
GCGR P47871 1/20 0.40
TLR8 Q9NR97 1/20 0.37
ICMT O60725 1/20 0.33
HDAC3 O15379 1/20 0.33
HDAC1 Q13547 1/20 0.33
HDAC2 Q92769 1/20 0.33
HDAC8 Q9BY41 1/20 0.33
HDAC6 Q9UBN7 1/20 0.33
MEN1 O00255 2/20 0.33
KMT2A Q03164 2/20 0.33
SMN1; SMN2 Q16637 2/20 0.33
LMNA P02545 1/20 0.33
ALDH1A1 P00352 2/20 0.32
MAPK1 P28482 1/20 0.32
HSD17B10 Q99714 1/20 0.32
NPC1 O15118 1/20 0.32
MITF O75030 1/20 0.32
GAA P10253 1/20 0.32
RAB9A P51151 1/20 0.32
L3MBTL1 Q9Y468 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL5715683 0.97 GCGR (0.39) GCGRTLR8ICMTHDAC3HDAC1
SCHEMBL5716067 0.97 GCGR (0.39) GCGRTLR8ICMTHDAC3HDAC1
SCHEMBL5715825 0.94 GCGR (0.39) GCGRTLR8HDAC3HDAC1HDAC2
SCHEMBL5716589 0.87 GCGR (0.36) GCGRTLR8HDAC3HDAC1HDAC2
SCHEMBL5716587 0.87 GCGR (0.35) GCGRTLR8LMNAALDH1A1MAPK1
SCHEMBL5715827 0.86 GCGR (0.37) GCGRTLR8HDAC3HDAC1HDAC2
SCHEMBL5716550 0.83 GCGR (0.36) GCGRTLR8ICMTNPC1MITF
SCHEMBL5716123 0.83 GCGR (0.39) GCGRTLR8HDAC3HDAC1HDAC2
SCHEMBL5715539 0.81 MEN1 (0.48) GCGRTLR8HDAC3HDAC1HDAC2
SCHEMBL5716039 0.81 MEN1 (0.48) GCGRTLR8HDAC3HDAC1HDAC2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1661900-A1 Olefin polymerization cocatalysts derived from group-15 cationic compounds and processes using them ExxonMobil Chemical Patents Inc. (US) 2006-05-31 EP disclosed
EP-1252166-B1 OLEFIN POLYMERIZATION COCATALYSTS DERIVED FROM GROUP-15 CATIONIC COMPOUNDS AND PROCESSES USING THEM EXXONMOBIL CHEM PATENTS INC (US) 2005-11-09 EP disclosed