SCHEMBL28839028

SCHEMBL28839028

Brc1cc(-c2cccc3c2[nH]c2ccccc23)c(-c2cccc3c2[nH]c2ccccc23)cc1Br

nearest known ligand 0.50

Predicted protein targets (top 8)

geneUniProtsupporting neighboursconfidence
PARP14 Q460N5 13/20 0.50
KIF11 P52732 4/20 0.50
IDO1 P14902 1/20 0.46
TDO2 P48775 1/20 0.46
BCHE P06276 1/20 0.45
ALDH1A1 P00352 1/20 0.45
GPR3 P46089 1/20 0.45
HSD17B10 Q99714 1/20 0.45

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL30084624 1.00 PARP14 (0.50) PARP14KIF11IDO1TDO2BCHE
SCHEMBL1683249 0.87 KIF11 (0.52) PARP14KIF11BCHEALDH1A1GPR3
SCHEMBL208113 0.87 KIF11 (0.63) PARP14KIF11BCHEALDH1A1GPR3
SCHEMBL29733506 0.87 KIF11 (0.63) PARP14KIF11BCHEALDH1A1GPR3
SCHEMBL30521516 0.85 KIF11 (0.61) PARP14KIF11BCHEALDH1A1GPR3
SCHEMBL191654 0.85 KIF11 (0.61) PARP14KIF11BCHEALDH1A1GPR3
SCHEMBL51674 0.85 KIF11 (0.61) PARP14KIF11BCHEALDH1A1GPR3
SCHEMBL3345110 0.84 PARP14 (0.49) PARP14KIF11BCHEALDH1A1GPR3
SCHEMBL15162688 0.83 AR (0.49) PARP14KIF11IDO1TDO2
Lithium SCHEMBL31282245 0.83 KIF11 (0.59) PARP14KIF11BCHEALDH1A1GPR3

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-115057887-A Dicarbazole phenyl diphosphine ligand and preparation method thereof, carbazole phenyl diphosphine cuprous halide and preparation method and application thereof 湖北大学 2022-09-16 CN disclosed