SCHEMBL2883909

SCHEMBL2883909

c1ccc2nc3ccoc3cc2c1

nearest known ligand 0.56

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MAPT P10636 6/20 0.56
ALDH1A1 P00352 5/20 0.56
HPGD P15428 5/20 0.56
GLA P06280 2/20 0.56
ACHE P22303 1/20 0.56
NQO2 P16083 2/20 0.43
HTR3A P46098 1/20 0.42
KMT2A Q03164 5/20 0.41
NPC1 O15118 4/20 0.41
RAB9A P51151 3/20 0.41
KDM4E B2RXH2 3/20 0.41
POLB P06746 3/20 0.41
GAA P10253 2/20 0.41
LMNA P02545 1/20 0.41
PTBP1 P26599 1/20 0.41
RCE1 Q9Y256 1/20 0.41
DYRK1A Q13627 1/20 0.40
MEN1 O00255 3/20 0.39
PKM P14618 2/20 0.39
HSD17B10 Q99714 2/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6652020 0.79 ALDH1A1 (0.56) MAPTALDH1A1HPGDGLAACHE
SCHEMBL7532714 0.76 ALDH1A1 (0.47) MAPTALDH1A1HPGDGLAACHE
Acridine SCHEMBL28032761 0.74 MAPT (0.88) MAPTALDH1A1HPGDGLAACHE
Acridine SCHEMBL4972293 0.74 ALDH1A1 (1.00) MAPTALDH1A1HPGDGLAACHE
Acridine SCHEMBL29352289 0.74 ALDH1A1 (1.00) MAPTALDH1A1HPGDGLAACHE
Acridine SCHEMBL1772714 0.74 ALDH1A1 (1.00) MAPTALDH1A1HPGDGLAACHE
Acridine SCHEMBL3045498 0.74 ALDH1A1 (1.00) MAPTALDH1A1HPGDGLAACHE
Acridine SCHEMBL8339 0.74 ALDH1A1 (1.00) MAPTALDH1A1HPGDGLAACHE
SCHEMBL11336569 0.73 ALDH1A1 (0.36) MAPTALDH1A1HPGDKMT2ANPC1
SCHEMBL29511331 0.72 DYRK1A (0.41) ACHEKDM4EDYRK1AHSD17B10

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 15 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2023025298-A1 QUINOLINOFURAN DERIVATIVE AND USE THEREOF 瑞石生物医药有限公司 2023-03-02 WO disclosed
WO-2023025298-A1 QUINOLINOFURAN DERIVATIVE AND USE THEREOF 瑞石生物医药有限公司 2023-03-02 WO disclosed
CN-108409747-B Synthetic method of 2-aminoquinoline dihydrofuran compound 华南理工大学 2021-09-21 CN disclosed
EP-2030792-B1 INKJET PRINTER AND IMAGE-FORMING METHOD KONICA MINOLTA MED & GRAPHIC (JP) 2013-01-02 EP disclosed
US-7824022-B2 Ink-jet printer and image forming method KONICA MINOLTA MEDICAL & GRAPHIC, INC. (JP) 2010-11-02 US disclosed
EP-2030792-A1 INKJET PRINTER AND IMAGE-FORMING METHOD Konica Minolta Medical & Graphic, Inc. (JP) 2009-03-04 EP disclosed
EP-1942159-A1 Two-part curable ink composition set and ink jet recording method, ink jet recording apparatus, and printed product using the same SEIKO EPSON CORPORATION (JP) 2008-07-09 EP disclosed
US-20080146689-A1 Two-part curable ink composition set and ink jet recording method, ink jet recording apparatus, and printed product using the same SEIKO EPSON CORPORATION 2008-06-19 US disclosed
US-20070296787-A1 Ink-jet printer and image forming method KONICA MINOLTA MEDICAL & GRAPHIC, INC. (JP) 2007-12-27 US disclosed
US-20070249750-A1 Two-part photocurable ink composition set and ink jet recording method, ink jet recording apparatus, and print using the same SEIKO EPSON CORPORATION 2007-10-25 US disclosed
EP-1197939-B1 ORIGINAL PLATE FOR DIAL, DIAL, AND METHOD FOR MANUFACTURING INDICATING DEVICE SEIKO EPSON CORP (JP) 2007-04-18 EP disclosed
US-6793977-B2 Method of manufacturing a display plate and display apparatus SEIKO EPSON CORPORATION (JP) 2004-09-21 US disclosed
US-20030210291-A1 Method of manufacturing a display plate and display apparatus KASAHARA SACHIO (JP) 2003-11-13 US disclosed
US-6599613-B1 Primitive display plate and method of manufacturing display plate and display apparatus SEIKO EPSON CORPORATION (JP) 2003-07-29 US disclosed
EP-1197939-A1 ORIGINAL PLATE FOR DIAL, DIAL, AND METHOD FOR MANUFACTURING INDICATING DEVICE SEIKO EPSON CORPORATION (JP) 2002-04-17 EP disclosed