Known targets — ChEMBL curated mechanism
ACHEADRA1AADRA1BADRA1DADRA2AADRA2BADRA2CADRB1ADRB2ADRB3APH1AAPH1BCHRM2CHRM3EZH2GRIN2AHTR1AHTR1BHTR1DHTR1FHTR3ANCSTNP2RY12PSEN1PSEN2PSENENSIGMAR1SLC6A2SLC6A3SLC6A4
The experimentally established mechanism targets of Cyproconazole. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 3/20 | 0.52 |
| ▸ | CYP3A4 | P08684 | 7/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.47 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.41 |
| ▸ | PDCD1 | Q15116 | 2/20 | 0.40 |
| ▸ | CD274 | Q9NZQ7 | 2/20 | 0.40 |
| ▸ | CYP2C9 | P11712 | 5/20 | 0.40 |
| ▸ | CYP2C19 | P33261 | 5/20 | 0.40 |
| ▸ | CYP1A2 | P05177 | 3/20 | 0.40 |
| ▸ | CYP2D6 | P10635 | 3/20 | 0.40 |
| ▸ | KCNH2 | Q12809 | 2/20 | 0.40 |
| ▸ | CYP2B6 | P20813 | 1/20 | 0.37 |
| ▸ | CYP3A5 | P20815 | 1/20 | 0.37 |
| ▸ | CYP3A7 | P24462 | 1/20 | 0.37 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.37 |
| ▸ | CYP3A43 | Q9HB55 | 1/20 | 0.37 |
| ▸ | CYP46A1 | Q9Y6A2 | 1/20 | 0.37 |
| ▸ | LMNA | P02545 | 1/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.37 |
| ▸ | POLB | P06746 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Cyproconazole SCHEMBL28950859 | 0.99 | KMT2A (0.53) | KMT2ACYP3A4ALDH1A1HSP90AA1PDCD1 | |
| Cyproconazole SCHEMBL20791 | 0.99 | KMT2A (0.53) | KMT2ACYP3A4ALDH1A1HSP90AA1PDCD1 | |
| Cyproconazole SCHEMBL3685487 | 0.99 | KMT2A (0.53) | KMT2ACYP3A4ALDH1A1HSP90AA1PDCD1 | |
| Cyproconazole SCHEMBL13014891 | 0.99 | KMT2A (0.53) | KMT2ACYP3A4ALDH1A1HSP90AA1PDCD1 | |
| Cyproconazole SCHEMBL23532643 | 0.98 | KMT2A (0.52) | KMT2ACYP3A4ALDH1A1HSP90AA1PDCD1 | |
| Cyproconazole SCHEMBL27846722 | 0.98 | KMT2A (0.52) | KMT2ACYP3A4ALDH1A1HSP90AA1PDCD1 | |
| Cyproconazole SCHEMBL28396979 | 0.98 | KMT2A (0.52) | KMT2ACYP3A4ALDH1A1HSP90AA1PDCD1 | |
| Cyproconazole SCHEMBL27820550 | 0.95 | KMT2A (0.53) | KMT2ACYP3A4ALDH1A1HSP90AA1PDCD1 | |
| Cyproconazole SCHEMBL28269063 | 0.92 | KMT2A (0.47) | KMT2ACYP3A4ALDH1A1HSP90AA1PDCD1 | |
| Cyproconazole SCHEMBL12475814 | 0.88 | KMT2A (0.43) | KMT2ACYP3A4ALDH1A1HSP90AA1PDCD1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115067345-A | Bactericidal composition, preparation and application thereof | 东莞市东阳光农药研发有限公司 | 2022-09-20 | — | — | CN | disclosed |