Cyproconazole

Cyproconazole

SCHEMBL3685487

CC(C1CC1)C(O)(Cn1cncn1)c1ccc(Cl)cc1.CC(C1CC1)C(O)(Cn1cncn1)c1ccc(Cl)cc1

nearest known ligand 0.53

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KMT2A Q03164 3/20 0.53
CYP3A4 P08684 7/20 0.48
ALDH1A1 P00352 1/20 0.48
HSP90AA1 P07900 1/20 0.42
PDCD1 Q15116 2/20 0.41
CD274 Q9NZQ7 2/20 0.41
CYP2C9 P11712 5/20 0.40
CYP2C19 P33261 5/20 0.40
CYP1A2 P05177 3/20 0.40
CYP2D6 P10635 3/20 0.40
KCNH2 Q12809 2/20 0.40
CYP2B6 P20813 1/20 0.38
CYP3A5 P20815 1/20 0.38
CYP3A7 P24462 1/20 0.38
MAPK1 P28482 1/20 0.38
CYP3A43 Q9HB55 1/20 0.38
CYP46A1 Q9Y6A2 1/20 0.38
LMNA P02545 1/20 0.38
KDM4E B2RXH2 1/20 0.38
POLB P06746 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Cyproconazole SCHEMBL13014891 1.00 KMT2A (0.53) KMT2ACYP3A4ALDH1A1HSP90AA1PDCD1
Cyproconazole SCHEMBL20791 1.00 KMT2A (0.53) KMT2ACYP3A4ALDH1A1HSP90AA1PDCD1
Cyproconazole SCHEMBL28950859 1.00 KMT2A (0.53) KMT2ACYP3A4ALDH1A1HSP90AA1PDCD1
Cyproconazole SCHEMBL23532643 0.99 KMT2A (0.52) KMT2ACYP3A4ALDH1A1HSP90AA1PDCD1
Cyproconazole SCHEMBL28839157 0.99 KMT2A (0.52) KMT2ACYP3A4ALDH1A1HSP90AA1PDCD1
Cyproconazole SCHEMBL28396979 0.99 KMT2A (0.52) KMT2ACYP3A4ALDH1A1HSP90AA1PDCD1
Cyproconazole SCHEMBL12475814 0.89 KMT2A (0.43) KMT2ACYP3A4ALDH1A1HSP90AA1PDCD1
Cyproconazole SCHEMBL8463921 0.89 KMT2A (0.43) KMT2ACYP3A4ALDH1A1HSP90AA1PDCD1
Cyproconazole SCHEMBL8164442 0.87 KMT2A (0.42) KMT2ACYP3A4ALDH1A1HSP90AA1PDCD1
Cyproconazole SCHEMBL2555661 0.87 KMT2A (0.42) KMT2ACYP3A4ALDH1A1HSP90AA1PDCD1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20100305161-A1 COMBINATIONS OF FUNGICIDAL AZOLES AND PYRION COMPOUNDS BOSSELAERS JAN PETER HENDRIK 2010-12-02 US disclosed
CN-101877968-A Fungicidal azole compounds and pyrion combination of compounds JANSSEN PHARMACEUTICA NV 2010-11-03 CN disclosed
US-7662748-B2 Such as azaconazole, bromuconazole, and N,N',N'-tris(2-hydroxyethyl)-N-cocoalkyl-1,3-diamino-propane; kits; for protection of crops, plants, fruits, seeds, wood products, thatch, biodegradable material and textiles JANSSEN PHARMACEUTICA, N.V. (BE) 2010-02-16 US disclosed
CN-100399897-C Formulations containing triazoles and alkoxylated amines JANSSEN PHARMACEUTICA NV (BE) 2008-07-09 CN disclosed
CN-1627900-A Formulations comprising triazoles and alkoxylated amines JANSSEN PHARMACEUTICA NV (BE) 2005-06-15 CN disclosed
US-20050080089-A1 Formulations comprising triazoles and alkoxylated amines AKZO NOBEL CHEMICALS BV (NL) 2005-04-14 US disclosed
US-5714507-A FUNGICIDE JANSSEN PHARMACEUTICA, N.V. (BE) 1998-02-03 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20050080089-A1 Formulations comprising triazoles and alkoxylated amines ALKBH3, TYR, NAT1 KMT2A 1163/4885CYP3A4 100/4885ALDH1A1 469/4885
US-20100305161-A1 COMBINATIONS OF FUNGICIDAL AZOLES AND PYRION COMPOUNDS PPOX, PNPO, CYP3A43 KMT2A 4343/4885CYP3A4 7/4885ALDH1A1 1720/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.