Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NAMPT | P43490 | 1/20 | 0.38 |
| ▸ | HTT | P42858 | 2/20 | 0.36 |
| ▸ | FDPS | P14324 | 1/20 | 0.36 |
| ▸ | RAB9A | P51151 | 5/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.35 |
| ▸ | NPC1 | O15118 | 4/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.35 |
| ▸ | POLB | P06746 | 2/20 | 0.35 |
| ▸ | MAPT | P10636 | 2/20 | 0.35 |
| ▸ | MEN1 | O00255 | 2/20 | 0.35 |
| ▸ | TP53 | P04637 | 1/20 | 0.35 |
| ▸ | HPGD | P15428 | 1/20 | 0.35 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.35 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.35 |
| ▸ | TSHR | P16473 | 1/20 | 0.35 |
| ▸ | ALPL | P05186 | 1/20 | 0.33 |
| ▸ | ALPG | P10696 | 1/20 | 0.33 |
| ▸ | LPO | P22079 | 1/20 | 0.33 |
| ▸ | GAA | P10253 | 2/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15979655 | 0.86 | NAMPT (0.44) | NAMPTHTTFDPSRAB9AALDH1A1 | |
| SCHEMBL12934353 | 0.79 | NAMPT (0.40) | NAMPTHTTFDPSRAB9AALDH1A1 | |
| SCHEMBL23745232 | 0.78 | STING1 (0.39) | NAMPTHTTFDPSRAB9AALDH1A1 | |
| SCHEMBL24096159 | 0.78 | NAMPT (0.39) | NAMPTHTTFDPSRAB9AALDH1A1 | |
| SCHEMBL12094827 | 0.77 | NAMPT (0.43) | NAMPTHTTFDPSRAB9AALDH1A1 | |
| SCHEMBL23891658 | 0.77 | NAMPT (0.38) | NAMPTHTTFDPSRAB9AALDH1A1 | |
| SCHEMBL18787644 | 0.76 | NAMPT (0.39) | NAMPTHTTFDPSRAB9AALDH1A1 | |
| SCHEMBL13319132 | 0.75 | PLOD2 (0.46) | NAMPTHTTFDPSRAB9AALDH1A1 | |
| SCHEMBL4865756 | 0.75 | NAMPT (0.42) | NAMPTHTTFDPSRAB9AALDH1A1 | |
| Hydrochloric Acid SCHEMBL1981157 | 0.75 | NAMPT (0.42) | NAMPTHTTFDPSRAB9AALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-110511259-B | Cyclic dinucleotide artificial metalloenzyme, preparation thereof and application thereof in catalyzing asymmetric Friedel-Crafts reaction | 陕西师范大学 | 2022-08-16 | — | — | CN | disclosed |