Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.65 |
| ▸ | ANPEP | P15144 | 3/20 | 0.61 |
| ▸ | ATM | Q13315 | 2/20 | 0.60 |
| ▸ | MAPT | P10636 | 2/20 | 0.55 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.55 |
| ▸ | GAA | P10253 | 2/20 | 0.54 |
| ▸ | POLB | P06746 | 1/20 | 0.54 |
| ▸ | LMNA | P02545 | 1/20 | 0.54 |
| ▸ | MME | P08473 | 1/20 | 0.52 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.51 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.51 |
| ▸ | RAB9A | P51151 | 1/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28839600 | 1.00 | ALDH1A1 (0.65) | ALDH1A1ANPEPATMMAPTL3MBTL1 | |
| SCHEMBL2563448 | 0.87 | ALDH1A1 (0.83) | ALDH1A1ANPEPATML3MBTL1GAA | |
| SCHEMBL8022139 | 0.87 | ALDH1A1 (0.83) | ALDH1A1ANPEPATML3MBTL1GAA | |
| SCHEMBL8088658 | 0.85 | ALDH1A1 (0.63) | ALDH1A1ANPEPATMMAPTL3MBTL1 | |
| SCHEMBL13559295 | 0.83 | NAALAD2 (0.71) | ALDH1A1ANPEPATMGAA | |
| SCHEMBL4770866 | 0.83 | ANPEP (0.79) | ALDH1A1ANPEPATMMAPTL3MBTL1 | |
| SCHEMBL4770883 | 0.83 | ANPEP (0.79) | ALDH1A1ANPEPATMMAPTL3MBTL1 | |
| SCHEMBL9554537 | 0.81 | ALDH1A1 (0.80) | ALDH1A1ANPEPATML3MBTL1GAA | |
| SCHEMBL7128474 | 0.80 | ALDH1A1 (0.58) | ALDH1A1ANPEPATM | |
| SCHEMBL2722853 | 0.80 | ALDH1A1 (0.58) | ALDH1A1ANPEPATMMAPTL3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-114736197-B | Imidazolidinone derivatives and their use | 南京医工医药技术有限公司 | 2022-09-13 | — | — | CN | disclosed |
| CN-114736197-A | Imidazolidinone derivatives and their use | 南京医工医药技术有限公司 | 2022-07-12 | — | — | CN | disclosed |