Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BCL2 | P10415 | 14/20 | 0.51 |
| ▸ | BCL2L1 | Q07817 | 3/20 | 0.51 |
| ▸ | BCL2A1 | Q16548 | 3/20 | 0.46 |
| ▸ | BID | P55957 | 2/20 | 0.45 |
| ▸ | MCL1 | Q07820 | 2/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.42 |
| ▸ | MEN1 | O00255 | 1/20 | 0.42 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.39 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.39 |
| ▸ | CDK8 | P49336 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28380007 | 0.91 | BCL2 (0.48) | BCL2BCL2L1BCL2A1BIDMCL1 | |
| SCHEMBL19867786 | 0.91 | BCL2 (0.50) | BCL2BCL2L1BCL2A1BIDMCL1 | |
| SCHEMBL1702063 | 0.89 | BCL2 (0.50) | BCL2BCL2L1BCL2A1BIDMCL1 | |
| SCHEMBL19692603 | 0.89 | BCL2 (0.55) | BCL2BCL2L1BCL2A1BIDMCL1 | |
| SCHEMBL28388778 | 0.88 | BCL2 (0.49) | BCL2BCL2L1BCL2A1BIDMCL1 | |
| SCHEMBL23323413 | 0.84 | BCL2 (0.55) | BCL2BCL2L1BCL2A1 | |
| SCHEMBL30415477 | 0.84 | BCL2 (0.55) | BCL2BCL2L1BCL2A1 | |
| SCHEMBL12067449 | 0.84 | BCL2A1 (0.54) | BCL2BCL2L1BCL2A1BIDMCL1 | |
| SCHEMBL33530380 | 0.84 | BCL2A1 (0.54) | BCL2BCL2L1BCL2A1BIDMCL1 | |
| SCHEMBL25241505 | 0.84 | BCL2 (0.51) | BCL2BCL2L1BCL2A1BIDMCL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115043833-B | Bcl-2 fluorescent probe and preparation method and application thereof | 山东大学 | 2024-01-12 | — | — | CN | disclosed |
| CN-115043833-A | Bcl-2 fluorescent probe and preparation method and application thereof | 山东大学 | 2022-09-13 | — | — | CN | disclosed |