Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.51 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.51 |
| ▸ | MAPT | P10636 | 1/20 | 0.51 |
| ▸ | NPC1 | O15118 | 4/20 | 0.47 |
| ▸ | RAB9A | P51151 | 3/20 | 0.47 |
| ▸ | GLA | P06280 | 2/20 | 0.46 |
| ▸ | TP53 | P04637 | 1/20 | 0.46 |
| ▸ | CASP1 | P29466 | 1/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.44 |
| ▸ | GAA | P10253 | 1/20 | 0.44 |
| ▸ | POLB | P06746 | 1/20 | 0.43 |
| ▸ | LRRK2 | Q5S007 | 1/20 | 0.43 |
| ▸ | EGLN1 | Q9GZT9 | 2/20 | 0.42 |
| ▸ | PKM | P14618 | 1/20 | 0.42 |
| ▸ | HPGD | P15428 | 1/20 | 0.42 |
| ▸ | BRCA1 | P38398 | 1/20 | 0.42 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.41 |
| ▸ | PDCD1 | Q15116 | 1/20 | 0.41 |
| ▸ | CD274 | Q9NZQ7 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29175523 | 0.86 | MAPT (0.47) | ALDH1A1SMN1; SMN2MAPTNPC1RAB9A | |
| SCHEMBL28840064 | 0.85 | EGLN1 (0.50) | ALDH1A1SMN1; SMN2MAPTKDM4ELRRK2 | |
| SCHEMBL28840065 | 0.83 | EGLN1 (0.48) | SMN1; SMN2MAPTRAB9AKDM4EPOLB | |
| SCHEMBL1823015 | 0.82 | MIF (0.44) | ALDH1A1SMN1; SMN2KDM4EGAALRRK2 | |
| SCHEMBL24994150 | 0.80 | ALDH1A1 (0.55) | ALDH1A1SMN1; SMN2MAPTNPC1RAB9A | |
| SCHEMBL29175526 | 0.80 | ALDH1A1 (0.55) | ALDH1A1SMN1; SMN2MAPTNPC1RAB9A | |
| SCHEMBL30233561 | 0.80 | ALDH1A1 (0.55) | ALDH1A1SMN1; SMN2MAPTNPC1RAB9A | |
| SCHEMBL13634462 | 0.79 | CNR1 (0.44) | SMN1; SMN2LRRK2EGLN1 | |
| SCHEMBL286232 | 0.79 | CA12 (0.49) | ALDH1A1SMN1; SMN2MAPTGLATP53 | |
| SCHEMBL13161985 | 0.78 | EGLN1 (0.52) | SMN1; SMN2RAB9APOLBLRRK2EGLN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-114907236-B | Aldoxime compound and preparation method and application thereof | 四川青木制药有限公司 | 2024-02-09 | — | — | CN | disclosed |
| CN-114907236-A | Aldoxime compound and preparation method and application thereof | 四川青木制药有限公司 | 2022-08-16 | — | — | CN | disclosed |