SCHEMBL28839786

SCHEMBL28839786

Cc1cc(Br)ccc1C(=O)NCC(=O)OC(C)C

nearest known ligand 0.44

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
FLT1 P17948 1/20 0.42
FLT4 P35916 1/20 0.42
KDR P35968 1/20 0.42
NLRP3 Q96P20 1/20 0.41
GPR27 Q9NS67 1/20 0.41
TRPV1 Q8NER1 1/20 0.41
PSMB11 A5LHX3 1/20 0.40
PSMA7 O14818 1/20 0.40
PSMB1 P20618 1/20 0.40
PSMA1 P25786 1/20 0.40
PSMA2 P25787 1/20 0.40
PSMA3 P25788 1/20 0.40
PSMA4 P25789 1/20 0.40
PSMB8 P28062 1/20 0.40
PSMB9 P28065 1/20 0.40
PSMA5 P28066 1/20 0.40
PSMB4 P28070 1/20 0.40
PSMB6 P28072 1/20 0.40
PSMB5 P28074 1/20 0.40
PSMB10 P40306 1/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29175526 0.83 ALDH1A1 (0.55) FLT1FLT4KDRALDH1A1KDM4E
SCHEMBL28840064 0.81 EGLN1 (0.50) NLRP3ALDH1A1KDM4ESMN1; SMN2LMNA
SCHEMBL28840307 0.80 EGLN1 (0.51) FLT1FLT4KDRGPR27TRPV1
SCHEMBL22859142 0.77 FLT1 (0.46) FLT1FLT4KDRGPR27TRPV1
SCHEMBL22859172 0.77 FLT1 (0.46) FLT1FLT4KDRGPR27TRPV1
SCHEMBL22859136 0.77 FLT1 (0.46) FLT1FLT4KDRGPR27TRPV1
SCHEMBL4525917 0.76 CA12 (0.51) FLT1FLT4KDRGPR27ALDH1A1
SCHEMBL26905965 0.76 HTT (0.54) FLT1FLT4KDRGPR27TRPV1
SCHEMBL3658275 0.76 FLT1 (0.50) FLT1FLT4KDRGPR27TRPV1
SCHEMBL22859168 0.74 TRPV1 (0.40) FLT1FLT4KDRGPR27TRPV1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-114907236-A Aldoxime compound and preparation method and application thereof 四川青木制药有限公司 2022-08-16 CN disclosed