SCHEMBL28839983

SCHEMBL28839983

O=C(CC1CNCCO1)Oc1ccccc1

nearest known ligand 0.45

Predicted protein targets (top 11)

geneUniProtsupporting neighboursconfidence
MIF P14174 1/20 0.45
SLC6A2 P23975 11/20 0.45
SLC6A3 Q01959 7/20 0.45
SLC6A4 P31645 7/20 0.45
ADRB2 P07550 1/20 0.45
HTR1A P08908 1/20 0.45
HTR2A P28223 1/20 0.45
ADRA1A P35348 1/20 0.45
HTR2B P41595 1/20 0.45
ADRA2C P18825 1/20 0.45
CHEK1 O14757 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL28839987 0.88 SLC6A2 (0.44) SLC6A2SLC6A3SLC6A4ADRB2HTR1A
SCHEMBL23286062 0.81 GLA (0.50) SLC6A2SLC6A3SLC6A4ADRB2HTR1A
Hydrochloric Acid SCHEMBL29854262 0.80 GLA (0.49) SLC6A2SLC6A3SLC6A4ADRB2HTR1A
SCHEMBL3159173 0.78 KMT2A (0.46) SLC6A2SLC6A3SLC6A4ADRB2HTR1A
SCHEMBL11627466 0.77 MIF (0.47) MIFHTR2A
SCHEMBL17028386 0.75 SSTR4 (0.43) SLC6A2SLC6A3SLC6A4
SCHEMBL17237648 0.75 EPHX2 (0.48) CHEK1
SCHEMBL2925939 0.75 HTR2A (0.65) SLC6A2SLC6A3SLC6A4ADRB2HTR1A
SCHEMBL1002267 0.75 HTR2A (0.65) SLC6A2SLC6A3SLC6A4ADRB2HTR1A
SCHEMBL2924439 0.75 HTR2A (0.65) SLC6A2SLC6A3SLC6A4ADRB2HTR1A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-114907288-A Application of nitrobenzene compounds in preparation of pseudomonas aeruginosa quorum sensing inhibitor 中国医学科学院医药生物技术研究所 2022-08-16 CN disclosed