SCHEMBL3159173

SCHEMBL3159173

O=C(CC1CNCCO1)c1ccccc1

nearest known ligand 0.47

Predicted protein targets (top 15)

geneUniProtsupporting neighboursconfidence
KMT2A Q03164 1/20 0.46
SLC6A2 P23975 11/20 0.45
SLC6A3 Q01959 8/20 0.45
SLC6A4 P31645 6/20 0.45
ADRB2 P07550 1/20 0.45
HTR1A P08908 1/20 0.45
HTR2A P28223 1/20 0.45
ADRA1A P35348 1/20 0.45
HTR2B P41595 1/20 0.45
ADRA2C P18825 1/20 0.45
ALDH1A1 P00352 1/20 0.42
MAPT P10636 1/20 0.42
L3MBTL1 Q9Y468 1/20 0.42
CHEK1 O14757 1/20 0.41
HPGD P15428 1/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL5985191 0.85 SLC6A2 (0.37) SLC6A2SLC6A3SLC6A4ADRB2HTR1A
SCHEMBL28876749 0.85 GSK3B (0.41) KMT2ASLC6A2SLC6A3SLC6A4ADRB2
SCHEMBL27793843 0.84 KMT2A (0.52) KMT2ASLC6A2SLC6A3SLC6A4ADRB2
SCHEMBL11319508 0.81 GSK3B (0.46) KMT2AALDH1A1MAPTHPGD
SCHEMBL7715189 0.80 CHEK1 (0.33) KMT2ASLC6A2SLC6A3SLC6A4ADRB2
Benzoic Acid SCHEMBL11711296 0.79 SLC6A2 (0.49) SLC6A2SLC6A3SLC6A4ADRB2HTR1A
SCHEMBL28839983 0.78 MIF (0.45) SLC6A2SLC6A3SLC6A4ADRB2HTR1A
SCHEMBL17237648 0.78 EPHX2 (0.48) CHEK1
SCHEMBL31188587 0.78 HPGD (0.64) KMT2ASLC6A2SLC6A4ALDH1A1CHEK1
SCHEMBL2439612 0.78 HPGD (0.64) KMT2ASLC6A2SLC6A4ALDH1A1CHEK1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 27 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-111620845-A Long-wavelength morpholinyl acetophenone photoinitiator and preparation method thereof 北京化工大学常州先进材料研究院 2020-09-04 CN claimed
CN-111499595-A Novel morpholinyl acetophenone photoinitiator and preparation method thereof 北京化工大学常州先进材料研究院 2020-08-07 CN claimed
CN-114031477-A Method for reducing amide compounds into amine compounds by cobalt catalysis 浙江工业大学 2022-02-11 CN disclosed
CN-111620845-A Long-wavelength morpholinyl acetophenone photoinitiator and preparation method thereof 北京化工大学常州先进材料研究院 2020-09-04 CN disclosed
CN-111620845-A Long-wavelength morpholinyl acetophenone photoinitiator and preparation method thereof 北京化工大学常州先进材料研究院 2020-09-04 CN disclosed
CN-111620845-A Long-wavelength morpholinyl acetophenone photoinitiator and preparation method thereof 北京化工大学常州先进材料研究院 2020-09-04 CN disclosed
CN-111499595-A Novel morpholinyl acetophenone photoinitiator and preparation method thereof 北京化工大学常州先进材料研究院 2020-08-07 CN disclosed
CN-111499595-A Novel morpholinyl acetophenone photoinitiator and preparation method thereof 北京化工大学常州先进材料研究院 2020-08-07 CN disclosed
CN-111499595-A Novel morpholinyl acetophenone photoinitiator and preparation method thereof 北京化工大学常州先进材料研究院 2020-08-07 CN disclosed
CN-107266328-B Oligomeric amino ketones and its purposes as photoinitiator 太阳化学公司 2019-11-19 CN disclosed
CN-109320429-A Oligomeric amino ketones and its purposes as photoinitiator 太阳化学公司 2019-02-12 CN disclosed
CN-1681763-A Chemical compounds ASTRAZENECA AB (SE) 2005-10-12 CN disclosed
EP-1091737-B1 Use of 1-(3,3-diphenylpropionyl)-4-benzhydril piperazine in the treatment of pain NEUROMED TECH INC (CA) 2005-09-14 EP disclosed
EP-1549600-A1 KETONES AstraZeneca AB (SE) 2005-07-06 EP disclosed
EP-1466605-A2 Calcium channel blockers Neuromed Technologies Inc. (CA) 2004-10-13 EP disclosed
WO-2004011410-A1 CHEMICAL COMPOUNDS ASTRAZENECA AB (SE) 2004-02-05 WO disclosed
US-6294533-B1 COMPOUNDS FOR CARDIOVASCULAR DISORDERS, STROKES AND ANALGESICS NEUORMED TECHNOLOGIES, INC. (CA) 2001-09-25 US disclosed
EP-1091737-A2 CALCIUM CHANNEL BLOCKERS Neuromed Technologies Inc. (CA) 2001-04-18 EP disclosed
WO-2000001375-A2 CALCIUM CHANNEL BLOCKERS NEUROMED TECHNOLOGIES, INC. (CA) 2000-01-13 WO disclosed
US-6011035-A LIBRARIES OF THESE COMPOUNDS CAN ALSO BE USED TO IDENTIFY ANTAGONISTS FOR OTHER TARGETS. COMPOUNDS CONTAINING BENZHYDRIL AND 6-MEMBERED HETEROCYCLIC MOIETIES NEUROMED TECHNOLOGIES INC. (CA) 2000-01-04 US disclosed