Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 1/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.46 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.42 |
| ▸ | HCRTR2 | O43614 | 1/20 | 0.41 |
| ▸ | HTR2A | P28223 | 1/20 | 0.39 |
| ▸ | HTR2C | P28335 | 1/20 | 0.39 |
| ▸ | HTR2B | P41595 | 1/20 | 0.39 |
| ▸ | CHRM5 | P08912 | 4/20 | 0.39 |
| ▸ | CHRM3 | P20309 | 4/20 | 0.39 |
| ▸ | CHRM2 | P08172 | 4/20 | 0.39 |
| ▸ | CHRM1 | P11229 | 3/20 | 0.39 |
| ▸ | CHRM4 | P08173 | 3/20 | 0.39 |
| ▸ | OPRL1 | P41146 | 1/20 | 0.38 |
| ▸ | CHRNB2 | P17787 | 1/20 | 0.38 |
| ▸ | CHRNA7 | P36544 | 1/20 | 0.38 |
| ▸ | CHRNA4 | P43681 | 1/20 | 0.38 |
| ▸ | CCNT1 | O60563 | 1/20 | 0.38 |
| ▸ | CDK9 | P50750 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28840097 | 1.00 | MEN1 (0.46) | MEN1KMT2AKCNH2HCRTR2HTR2A | |
| SCHEMBL3333995 | 1.00 | MEN1 (0.46) | MEN1KMT2AKCNH2HCRTR2HTR2A | |
| SCHEMBL29749243 | 1.00 | MEN1 (0.46) | MEN1KMT2AKCNH2HCRTR2HTR2A | |
| Hydrochloric Acid SCHEMBL28593671 | 0.98 | MEN1 (0.45) | MEN1KMT2AKCNH2HCRTR2HTR2A | |
| Hydrochloric Acid SCHEMBL28593668 | 0.98 | MEN1 (0.45) | MEN1KMT2AKCNH2HCRTR2HTR2A | |
| SCHEMBL1765144 | 0.95 | MEN1 (0.42) | MEN1KMT2AKCNH2HCRTR2HTR2A | |
| SCHEMBL30423645 | 0.95 | MEN1 (0.42) | MEN1KMT2AKCNH2HCRTR2HTR2A | |
| SCHEMBL933161 | 0.86 | KDM1A (0.44) | MEN1KMT2AKCNH2HCRTR2HTR2A | |
| SCHEMBL22917359 | 0.86 | KDM1A (0.44) | MEN1KMT2AKCNH2HCRTR2HTR2A | |
| SCHEMBL932672 | 0.86 | KDM1A (0.44) | MEN1KMT2AKCNH2HCRTR2HTR2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-114907247-A | Preparation method of pyrrolidine intermediate and pyrrolidine salt compound | 上海陶术生物科技有限公司 | 2022-08-16 | — | — | CN | disclosed |