Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.51 |
| ▸ | HPGD | P15428 | 1/20 | 0.51 |
| ▸ | BRD4 | O60885 | 2/20 | 0.47 |
| ▸ | BRPF1 | P55201 | 1/20 | 0.44 |
| ▸ | ROCK2 | O75116 | 2/20 | 0.40 |
| ▸ | CREBBP | Q92793 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.36 |
| ▸ | TP53 | P04637 | 2/20 | 0.35 |
| ▸ | MAPT | P10636 | 2/20 | 0.35 |
| ▸ | GLA | P06280 | 1/20 | 0.35 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.35 |
| ▸ | THRB | P10828 | 1/20 | 0.35 |
| ▸ | IDO1 | P14902 | 1/20 | 0.35 |
| ▸ | RIPK1 | Q13546 | 1/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.35 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.35 |
| ▸ | CDC25A | P30304 | 1/20 | 0.35 |
| ▸ | LMNA | P02545 | 3/20 | 0.35 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31039941 | 1.00 | KDM4E (0.51) | KDM4EALDH1A1HPGDBRD4BRPF1 | |
| SCHEMBL28840532 | 1.00 | KDM4E (0.51) | KDM4EALDH1A1HPGDBRD4BRPF1 | |
| SCHEMBL5800676 | 0.81 | GAA (0.49) | KDM4EALDH1A1HPGDBRD4BRPF1 | |
| SCHEMBL4431229 | 0.81 | GAA (0.49) | KDM4EALDH1A1HPGDBRD4BRPF1 | |
| SCHEMBL4421212 | 0.79 | CYP1A2 (0.51) | KDM4EALDH1A1HPGDBRD4KMT2A | |
| SCHEMBL17677007 | 0.78 | ROCK2 (0.51) | ALDH1A1BRD4ROCK2KMT2ACYP3A4 | |
| SCHEMBL30977961 | 0.77 | BRD4 (0.54) | KDM4EALDH1A1HPGDBRD4BRPF1 | |
| SCHEMBL31039936 | 0.77 | BRD4 (0.54) | KDM4EALDH1A1HPGDBRD4BRPF1 | |
| SCHEMBL28840091 | 0.77 | BRD4 (0.54) | KDM4EALDH1A1HPGDBRD4BRPF1 | |
| SCHEMBL28840096 | 0.77 | BRD4 (0.54) | KDM4EALDH1A1HPGDBRD4BRPF1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-114907277-A | Process for asymmetric hydrogenation of quinoxalinones | 哈尔滨工业大学（深圳） | 2022-08-16 | — | — | CN | disclosed |