Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CDC25A | P30304 | 1/20 | 0.73 |
| ▸ | MCL1 | Q07820 | 5/20 | 0.64 |
| ▸ | TERT | O14746 | 4/20 | 0.60 |
| ▸ | ICMT | O60725 | 1/20 | 0.56 |
| ▸ | FABP4 | P15090 | 1/20 | 0.56 |
| ▸ | FABP5 | Q01469 | 1/20 | 0.56 |
| ▸ | CREBBP | Q92793 | 1/20 | 0.56 |
| ▸ | PLK1 | P53350 | 4/20 | 0.54 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.54 |
| ▸ | LMNA | P02545 | 1/20 | 0.54 |
| ▸ | TBXAS1 | P24557 | 1/20 | 0.53 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28370235 | 0.88 | CDC25A (0.73) | CDC25AMCL1TERTICMTPLK1 | |
| SCHEMBL15747729 | 0.87 | CDC25A (0.90) | CDC25AMCL1ICMTPLK1ALDH1A1 | |
| SCHEMBL2429439 | 0.86 | CDC25A (0.97) | CDC25AMCL1ICMTPLK1ALDH1A1 | |
| SCHEMBL29379289 | 0.85 | CDC25A (0.68) | CDC25AMCL1TERTICMTCREBBP | |
| SCHEMBL2465449 | 0.85 | CDC25A (0.68) | CDC25AMCL1TERTICMTCREBBP | |
| SCHEMBL15747697 | 0.85 | CDC25A (1.00) | CDC25AMCL1ICMTPLK1ALDH1A1 | |
| SCHEMBL9700510 | 0.85 | CDC25A (1.00) | CDC25AMCL1ICMTPLK1ALDH1A1 | |
| SCHEMBL29376139 | 0.84 | CDC25A (0.67) | CDC25AMCL1TERTICMTCREBBP | |
| SCHEMBL15747715 | 0.84 | CDC25A (0.80) | CDC25AMCL1ICMTCREBBPPLK1 | |
| SCHEMBL28370205 | 0.83 | CDC25A (0.67) | CDC25AMCL1TERTICMTPLK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-114907389-A | Boronic acid derivatives | 首药控股(北京)股份有限公司 | 2022-08-16 | — | — | CN | disclosed |