Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TLR9 | Q9NR96 | 1/20 | 0.50 |
| ▸ | MGLL | Q99685 | 10/20 | 0.47 |
| ▸ | AHR | P35869 | 1/20 | 0.44 |
| ▸ | KEAP1 | Q14145 | 1/20 | 0.43 |
| ▸ | PDPK1 | O15530 | 1/20 | 0.42 |
| ▸ | FAAH | O00519 | 2/20 | 0.40 |
| ▸ | BRD4 | O60885 | 1/20 | 0.40 |
| ▸ | TAF1 | P21675 | 1/20 | 0.40 |
| ▸ | BRPF1 | P55201 | 1/20 | 0.40 |
| ▸ | CREBBP | Q92793 | 1/20 | 0.40 |
| ▸ | CECR2 | Q9BXF3 | 1/20 | 0.40 |
| ▸ | BRD9 | Q9H8M2 | 1/20 | 0.40 |
| ▸ | NR3C1 | P04150 | 1/20 | 0.39 |
| ▸ | PGR | P06401 | 1/20 | 0.39 |
| ▸ | NR3C2 | P08235 | 1/20 | 0.39 |
| ▸ | AR | P10275 | 1/20 | 0.39 |
| ▸ | BACE1 | P56817 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28654673 | 0.81 | AHR (0.43) | AHRKEAP1PDPK1BRD4TAF1 | |
| SCHEMBL14861202 | 0.76 | AHR (0.36) | AHRKEAP1PDPK1BRD4TAF1 | |
| SCHEMBL19511453 | 0.72 | TLR9 (0.62) | TLR9MGLLFAAH | |
| SCHEMBL7229298 | 0.72 | AHR (0.42) | AHRKEAP1PDPK1BRD4TAF1 | |
| SCHEMBL16719842 | 0.72 | AHR (0.48) | AHRKEAP1PDPK1BRD4TAF1 | |
| SCHEMBL28340162 | 0.71 | TLR9 (0.50) | TLR9MGLLAHRFAAH | |
| SCHEMBL29386767 | 0.69 | TLR9 (0.64) | TLR9MGLLFAAH | |
| SCHEMBL152339 | 0.69 | TLR9 (0.64) | TLR9MGLLFAAH | |
| SCHEMBL29110625 | 0.69 | TLR9 (0.47) | TLR9MGLLPDPK1FAAH | |
| SCHEMBL121404 | 0.69 | TLR9 (1.00) | TLR9MGLLFAAH |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-114057694-B | Preparation method of 7-maleimide indole compound | 温州医科大学 | 2023-01-03 | — | — | CN | claimed |
| CN-114057694-A | Preparation method of 7-maleimide indole compound | 温州医科大学 | 2022-02-18 | — | — | CN | claimed |
| CN-114057694-B | Preparation method of 7-maleimide indole compound | 温州医科大学 | 2023-01-03 | — | — | CN | disclosed |
| CN-114057694-B | Preparation method of 7-maleimide indole compound | 温州医科大学 | 2023-01-03 | — | — | CN | disclosed |
| CN-114057694-B | Preparation method of 7-maleimide indole compound | 温州医科大学 | 2023-01-03 | — | — | CN | disclosed |
| CN-114174496-A | Compositions and methods for generating hair cells by inhibiting epigenetic targets | 频率医疗公司 | 2022-03-11 | — | — | CN | disclosed |
| CN-114057694-A | Preparation method of 7-maleimide indole compound | 温州医科大学 | 2022-02-18 | — | — | CN | disclosed |
| CN-114057694-A | Preparation method of 7-maleimide indole compound | 温州医科大学 | 2022-02-18 | — | — | CN | disclosed |
| CN-114057694-A | Preparation method of 7-maleimide indole compound | 温州医科大学 | 2022-02-18 | — | — | CN | disclosed |