Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.33 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.33 |
| ▸ | HPGD | P15428 | 1/20 | 0.33 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL186763 | 0.87 | — | — | |
| SCHEMBL347612 | 0.87 | ALDH1A1 (0.40) | ALDH1A1CYP2C9HPGDHSD17B10MEN1 | |
| Hydrogen Sulfide SCHEMBL17888872 | 0.84 | ALDH1A1 (0.39) | ALDH1A1CYP2C9HPGDHSD17B10MEN1 | |
| SCHEMBL346186 | 0.78 | ALDH1A1 (0.46) | ALDH1A1CYP2C9HPGDHSD17B10MEN1 | |
| SCHEMBL2460944 | 0.69 | — | — | |
| SCHEMBL2498447 | 0.69 | — | — | |
| SCHEMBL10004386 | 0.67 | KMT2A (0.52) | ALDH1A1HSD17B10MEN1KMT2A | |
| SCHEMBL4396250 | 0.65 | — | — | |
| SCHEMBL346674 | 0.65 | HRH3 (0.31) | ALDH1A1MEN1KMT2A | |
| SCHEMBL2924957 | 0.65 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115348872-A | Bifunctional agents for protein recruitment and/or degradation | 奥里尼斯生物科学股份有限公司 | 2022-11-15 | — | — | CN | disclosed |
| CN-115038448-A | Compounds that modulate protein recruitment and/or degradation | 奥里尼斯生物科学股份有限公司 | 2022-09-09 | — | — | CN | disclosed |
| CN-113365978-A | HTRA (hyper-stable T-receptor) inhibitor and CAGA (cytokine induced graga) inhibitor and application thereof | 普梭梅根公司 | 2021-09-07 | — | — | CN | disclosed |