Glycine

Glycine

SCHEMBL28840966

CCCn1ccnc1.NCC(=O)O

nearest known ligand 0.61

Full drug profile on Sugi Atlas →

Known targets — ChEMBL curated mechanism

ADORA1ADORA2AADORA2BADORA3PDE3APDE3BPDE4APDE4BPDE4CPDE4D

The experimentally established mechanism targets of Glycine. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.

Predicted protein targets (top 4)

geneUniProtsupporting neighboursconfidence
EGLN3 Q9H6Z9 1/20 0.61
ALDH1A1 P00352 1/20 0.55
TBXAS1 P24557 16/20 0.54
QPCT Q16769 1/20 0.48

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Glycine SCHEMBL31139367 0.90 TBXAS1 (0.62) EGLN3ALDH1A1TBXAS1QPCT
Bicarbonate SCHEMBL28194026 0.89 EGLN3 (0.63) EGLN3ALDH1A1TBXAS1
Acetic Acid SCHEMBL671185 0.87 EGLN3 (0.61) EGLN3ALDH1A1TBXAS1
Oxalic Acid SCHEMBL29142315 0.87 EGLN3 (0.61) EGLN3ALDH1A1TBXAS1
Gamma-Aminobutyric Acid SCHEMBL28221361 0.86 TBXAS1 (0.63) EGLN3ALDH1A1TBXAS1
Alanine SCHEMBL28129733 0.83 TBXAS1 (0.56) EGLN3ALDH1A1TBXAS1
SCHEMBL152066 0.83
SCHEMBL15333636 0.83 EGLN3 (0.56) EGLN3ALDH1A1TBXAS1QPCT
Trifluoroacetic Acid SCHEMBL16700918 0.81 EGLN3 (0.54) EGLN3ALDH1A1TBXAS1
Lactic Acid SCHEMBL15334027 0.81 TBXAS1 (0.57) EGLN3ALDH1A1TBXAS1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-106362549-B It is a kind of to trap nitric oxide production method using amino acid anionic functional ionic liquid 浙江大学 2019-10-08 CN claimed
CN-106362549-A Method for capturing nitric oxide by using amino acid anion functional ionic liquid 浙江大学 2017-02-01 CN claimed