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Benzenesulfonamide

Benzenesulfonamide

SCHEMBL2884172

Cc1cc(C)c2nc(C3CC3)n(Cc3ccc(C4(C(=O)O)C=C=CC4)s3)c2n1.NS(=O)(=O)c1ccccc1

nearest known ligand 0.35

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Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
▸ AGTR1 P30556 2/20 0.35
▸ AGTR2 P50052 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Trifluoromethanesulfonamide SCHEMBL2877173 0.91 AGTR1 (0.33) AGTR1AGTR2
Benzenesulfonamide SCHEMBL5031361 0.78 AGTR1 (0.36) AGTR1AGTR2
SCHEMBL245008 0.77 AGTR1 (0.38) AGTR1AGTR2
SCHEMBL244556 0.77 AGTR1 (0.41) AGTR1AGTR2
SCHEMBL2876441 0.76 AGTR1 (0.38) AGTR1AGTR2
P-Toluenesulfonamide SCHEMBL8706787 0.73 AGTR1 (0.34) AGTR1AGTR2
SCHEMBL8700740 0.72 AGTR1 (0.37) AGTR1AGTR2
P-Toluenesulfonamide SCHEMBL244006 0.71 AGTR1 (0.35) AGTR1AGTR2
Methanesulfonamide SCHEMBL5029375 0.70 AGTR1 (0.35) AGTR1AGTR2
Trifluoromethanesulfonamide SCHEMBL5031352 0.68 AGTR1 (0.33) AGTR1AGTR2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-1995002596-A1 AZACYCLIC-HETEROCYCLIC COMPOUNDS AS ANGIOTENSIN II RECEPTOR ANTAGONISTS PFIZER INC. (US) 1995-01-26 — — WO claimed
US-8551950-B2 Method of treatment or prophylaxis of inflammatory pain SPINIFEX PHARMACEUTICALS PTY LTD (AU) 2013-10-08 — — US disclosed
US-7828840-B2 Medical devices and methods for local delivery of angiotensin II type 2 receptor antagonists MED INSTITUTE, INC. (US) 2010-11-09 — — US disclosed
US-20090177267-A1 Medical devices and methods for local delivery of angiotensin II type 2 receptor antagonists WILMINGTON TRUST, NATIONAL ASSOCIATION, AS COLLATERAL AGENT 2009-07-09 — — US disclosed
WO-1995002596-A1 AZACYCLIC-HETEROCYCLIC COMPOUNDS AS ANGIOTENSIN II RECEPTOR ANTAGONISTS PFIZER INC. (US) 1995-01-26 — — WO disclosed